Literature DB >> 8324214

Clonal diseases of large granular lymphocytes.

T P Loughran1.   

Abstract

Three distinct clinical syndromes occur in patients with increased numbers of circulating LGL. Patients with T-LGL leukemia have clonal proliferations of CD3+ LGL typically associated with chronic neutropenia and autoimmune features. NK-LGL leukemia is characterized by clonal CD3- LGL proliferation with an acute clinical presentation marked by massive hepatosplenomegaly and systemic illness. However, most patients with increased numbers of CD3- LGL do not have clinical features of NK-LGL leukemia and have a chronic clinical course. X-linked gene analyses have supported a polyclonal LGL lymphocytosis in this syndrome. Further studies are needed to determine whether clonal progression can occur in these patients.

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Year:  1993        PMID： 8324214

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  121 in total

1.  Large granular lymphocytic leukemia in a mixed breed dog.

Authors:  K W Lau; S A Kruth; C E Thorn; W Vernau; P Moore
Journal:  Can Vet J       Date:  1999-10       Impact factor: 1.008

2.  Immunophenotypic analysis of the TCR-Vbeta repertoire in 98 persistent expansions of CD3(+)/TCR-alphabeta(+) large granular lymphocytes: utility in assessing clonality and insights into the pathogenesis of the disease.

Authors:  M Lima; J Almeida; A H Santos; M dos Anjos Teixeira; M C Alguero; M L Queirós; A Balanzategui; B Justiça; M Gonzalez; J F San Miguel; A Orfão
Journal:  Am J Pathol       Date:  2001-11       Impact factor: 4.307

3.  Concurrent Hodgkin's disease (mixed cellularity type) and T-cell chronic lymphocytic leukemia/prolymphocytic leukemia.

Authors:  A Miyata; K Kojima; T Yoshino; S Fujii; K Shinagawa; K Ichimura
Journal:  Int J Hematol       Date:  2001-02       Impact factor: 2.490

4.  Hematopoietic stem cell transplantation for T-cell large granular lymphocyte leukemia: a retrospective study of the European Society for Blood and Marrow Transplantation.

Authors:  T Marchand; T Lamy; H Finel; W Arcese; S Choquet; J Finke; A Huynh; G Irrera; D Karakasis; J Konopacki; J Lambert; M Michieli; H C Schouten; W Schroyens; G Sucak; J Tischer; E Vandenberghe; P Dreger
Journal:  Leukemia       Date:  2015-09-22       Impact factor: 11.528

5.  Antigen activation and impaired Fas-induced death-inducing signaling complex formation in T-large-granular lymphocyte leukemia.

Authors:  Jun Yang; P K Epling-Burnette; Jeffrey S Painter; Jianxiang Zou; Fanqi Bai; Sheng Wei; Thomas P Loughran
Journal:  Blood       Date:  2007-11-09       Impact factor: 22.113

Review 6.  Peripheral T-cell lymphoma.

Authors:  Wing Y Au; Raymond Liang
Journal:  Curr Oncol Rep       Date:  2002-09       Impact factor: 5.075

Review 7.  Advances in the Diagnosis and Treatment of Large Granular Lymphocytic Leukemia.

Authors:  HeeJin Cheon; Karolina H Dziewulska; Katharine B Moosic; Kristine C Olson; Alejandro A Gru; David J Feith; Thomas P Loughran
Journal:  Curr Hematol Malig Rep       Date:  2020-04       Impact factor: 3.952

8.  A critical role for DAP10 and DAP12 in CD8+ T cell-mediated tissue damage in large granular lymphocyte leukemia.

Authors:  Xianghong Chen; Fanqi Bai; Lubomir Sokol; Junmin Zhou; Amy Ren; Jeffrey S Painter; Jinhong Liu; David A Sallman; Y Ann Chen; Jeffrey A Yoder; Julie Y Djeu; Thomas P Loughran; Pearlie K Epling-Burnette; Sheng Wei
Journal:  Blood       Date:  2008-12-15       Impact factor: 22.113

9.  Close resemblance between chemokine receptor expression profiles of lymphoproliferative disease of granular lymphocytes and their normal counterparts in association with elevated serum concentrations of IP-10 and MIG.

Authors:  Kayoko Momose; Hideki Makishima; Toshiro Ito; Hideyuki Nakazawa; Shigetaka Shimodaira; Kendo Kiyosawa; Fumihiro Ishida
Journal:  Int J Hematol       Date:  2007-08       Impact factor: 2.490

Review 10.  Gene rearrangements and chromosomal translocations in T cell lymphoma--diagnostic applications and their limits.

Authors:  H Griesser
Journal:  Virchows Arch       Date:  1995       Impact factor: 4.064
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