Literature DB >> 8324011

p-maleimidophenyl isocyanate: a novel heterobifunctional linker for hydroxyl to thiol coupling.

M E Annunziato1, U S Patel, M Ranade, P S Palumbo.   

Abstract

p-Maleimidophenyl isocyanate (PMPI, 1) is a heterobifunctional cross-linking agent useful for thiol to hydroxyl coupling. Several maleimide-activated compounds were prepared and characterized and then shown to be reactive with thiol-containing proteins. Examples include activation of vitamin B12, digoxigenin, digitoxigenin, estradiol, progesterone, and some serine-containing peptides.

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Year:  1993        PMID： 8324011     DOI： 10.1021/bc00021a005

Source DB:  PubMed          Journal:  Bioconjug Chem        ISSN： 1043-1802            Impact factor:   4.774


  10 in total

1.  Multifunctional Polymer-Coated Carbon Nanotubes for Safe Drug Delivery.

Authors:  Thomas L Moore; Joshua E Pitzer; Ramakrishna Podila; Xiaojia Wang; Robert L Lewis; Stuart W Grimes; James R Wilson; Even Skjervold; Jared M Brown; Apparao Rao; Frank Alexis
Journal:  Part Part Syst Charact       Date:  2013-02-28       Impact factor: 3.310

2.  Injectable Polymeric Cytokine-Binding Nanowires Are Effective Tissue-Specific Immunomodulators.

Authors:  Colin R Zamecnik; Margaret M Lowe; David M Patterson; Michael D Rosenblum; Tejal A Desai
Journal:  ACS Nano       Date:  2017-11-15       Impact factor: 15.881

3.  DNA-functionalized MFe2O4 (M = Fe, Co, or Mn) nanoparticles and their hybridization to DNA-functionalized surfaces.

Authors:  David B Robinson; Henrik H J Persson; Hao Zeng; Guanxiong Li; Nader Pourmand; Shouheng Sun; Shan X Wang
Journal:  Langmuir       Date:  2005-03-29       Impact factor: 3.882

4.  Labeling primary amine groups in peptides and proteins with N-hydroxysuccinimidyl ester modified Fe3O4@SiO2 nanoparticles containing cleavable disulfide-bond linkers.

Authors:  Ujwal S Patil; Haiou Qu; Daniela Caruntu; Charles J O'Connor; Arjun Sharma; Yang Cai; Matthew A Tarr
Journal:  Bioconjug Chem       Date:  2013-08-28       Impact factor: 4.774

5.  Cellular and Molecular Probing of Intact Human Organs.

Authors:  Shan Zhao; Mihail Ivilinov Todorov; Ruiyao Cai; Rami Ai -Maskari; Hanno Steinke; Elisabeth Kemter; Hongcheng Mai; Zhouyi Rong; Martin Warmer; Karen Stanic; Oliver Schoppe; Johannes Christian Paetzold; Benno Gesierich; Milagros N Wong; Tobias B Huber; Marco Duering; Oliver Thomas Bruns; Bjoern Menze; Jan Lipfert; Victor G Puelles; Eckhard Wolf; Ingo Bechmann; Ali Ertürk
Journal:  Cell       Date:  2020-02-13       Impact factor: 41.582

6.  Synthesis of a covalent epirubicin-(C(3)-amide)-anti-HER2/neu immunochemotherapeutic utilizing a UV-photoactivated anthracycline intermediate.

Authors:  Cody P Coyne; Toni Jones; Ryan Bear
Journal:  Cancer Biother Radiopharm       Date:  2011-12-22       Impact factor: 3.099

7.  X-ray photoelectron spectroscopy and infrared spectroscopy study of maleimide-activated supports for immobilization of oligodeoxyribonucleotides.

Authors:  Gang Shen; Maria Francis G Anand; Rastislav Levicky
Journal:  Nucleic Acids Res       Date:  2004-11-10       Impact factor: 16.971

8.  Chain Conformations at the Surface of a Polydisperse Amphiphilic Comb Copolymer Film.

Authors:  William A Kuhlman; Elsa A Olivetti; Linda G Griffith; Anne M Mayes
Journal:  Macromolecules       Date:  2006-07-25       Impact factor: 5.985

9.  Influence of Alternative Tubulin Inhibitors on the Potency of a Epirubicin-Immunochemotherapeutic Synthesized with an Ultra Violet Light-Activated Intermediate: Influence of incorporating an internal/integral disulfide bond structure and Alternative Tubulin/Microtubule Inhibitors on the Cytotoxic Anti-Neoplastic Potency of Epirubicin-(C3-amide)-Anti-HER2/neu Synthesized Utilizing a UV-Photoactivated Anthracycline Intermediate.

Authors:  C P Coyne; Toni Jones; Ryan Bear
Journal:  Cancer Clin Oncol       Date:  2012-11

10.  Synthesis of Gemcitabine-(C4-amide)-[anti-HER2/neu] Utilizing a UV-Photoactivated Gemcitabine Intermediate: Cytotoxic Anti-Neoplastic Activity against Chemotherapeutic-Resistant Mammary Adenocarcinoma SKBr-3.

Authors:  Cody P Coyne; Toni Jones; Ryan Bear
Journal:  J Cancer Ther       Date:  2012-10
  10 in total

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