Literature DB >> 8322247

Effect of preservative on the efficacy of terbutaline nebuliser solution in atopic asthma.

C K Lai1, C H Chan.   

Abstract

The efficacy of bronchodilator nebuliser solutions may be influenced by the presence of preservatives. In a double blind, randomised, crossover study the effect of preservatives in determining the airway responses to 5 mg of terbutaline was studied in a group of 21 atopic asthmatic patients. The presence of preservatives affected neither the bronchodilator action of terbutaline nor its protection against bronchoconstriction induced by histamine.

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Year:  1993        PMID: 8322247      PMCID: PMC464521          DOI: 10.1136/thx.48.5.566

Source DB:  PubMed          Journal:  Thorax        ISSN: 0040-6376            Impact factor:   9.139


  9 in total

1.  A non-bronchoconstrictor, bacteriostatic preservative for nebuliser solutions.

Authors:  Q A Summers; M R Nesbit; R Levin; S T Holgate
Journal:  Br J Clin Pharmacol       Date:  1991-02       Impact factor: 4.335

2.  Adverse reactions to the non-drug constituents of nebuliser solutions.

Authors:  R Beasley; P Rafferty; S T Holgate
Journal:  Br J Clin Pharmacol       Date:  1988-03       Impact factor: 4.335

3.  Effect of 15-(s)-hydroxyeicosatetraenoic acid on allergen-induced asthmatic responses.

Authors:  C K Lai; R Polosa; S T Holgate
Journal:  Am Rev Respir Dis       Date:  1990-06

4.  Use of bronchial provocation with histamine to compare the pharmacodynamics of inhaled albuterol and metaproterenol in patients with asthma.

Authors:  R C Ahrens; J B Harris; G Milavetz; L Annis; R Ries
Journal:  J Allergy Clin Immunol       Date:  1987-06       Impact factor: 10.793

5.  A method for comparing the peak intensity and duration of action of aerosolized bronchodilators using bronchoprovocation with methacholine.

Authors:  R C Ahrens; A C Bonham; G A Maxwell; M M Weinberger
Journal:  Am Rev Respir Dis       Date:  1984-06

6.  Methacholine dose-response curves in normal and asthmatic man: effect of starting conductance and pharmacological antagonism.

Authors:  K F Chung; P D Snashall
Journal:  Clin Sci (Lond)       Date:  1984-06       Impact factor: 6.124

7.  Effect of aerosol fenoterol on the severity of bronchial hyperreactivity in patients with asthma.

Authors:  C M Salome; R E Schoeffel; K Yan; A J Woolcock
Journal:  Thorax       Date:  1983-11       Impact factor: 9.139

8.  Bronchoconstrictor properties of preservatives in ipratropium bromide (Atrovent) nebuliser solution.

Authors:  C R Beasley; P Rafferty; S T Holgate
Journal:  Br Med J (Clin Res Ed)       Date:  1987-05-09

9.  Dose related effects of salbutamol and ipratropium bromide on airway calibre and reactivity in subjects with asthma.

Authors:  J Britton; S P Hanley; H V Garrett; J W Hadfield; A E Tattersfield
Journal:  Thorax       Date:  1988-04       Impact factor: 9.139

  9 in total

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