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Literature DB >> 832195

Glucose-glucagon relationships in adult sheep.

Abstract

Glucose-glucagon relationships were examined in adult sheep. Hyperglycemia was induced by infusing glucose at 120 mg/hr/kg body weight. Hypoglycemia was obtained by infusing insulin at 1.2 U/hr. In several experiments glucose at 40 mg/hr/kg was infused with insulin to obtain hyperinsulinemia without hypoglycemia to distinguish glucose-insulin effects. Glucagon concentrations decreased during hyperglycemia and increased during hypoglycemia. This study indicates that glucose-glucagon interactions may be important in regulation of glucagon secretion in sheep.

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Year: 1977 PMID： 832195 PMCID： PMC1277698

Source DB: PubMed Journal: Can J Comp Med ISSN： 0008-4050

15 in total

6. Plasma glucagon concentrations in sheep: their regulation and relation to concentrations of insulin and growth hormone.

Authors: J M Bassett
Journal: Aust J Biol Sci Date: 1972-12

7. Separation of pancreatic and gut glucagon-like immunoreactivity (G.L.I.) with observations on plasma concentrations of these hormones during lactation.

Authors: J G Manns
Journal: Can J Physiol Pharmacol Date: 1972-06 Impact factor: 2.273

Glucose-glucagon relationships in adult sheep.

1. Measurements of endogenous glucagon in plasma and the influence of blood glucose concentration upon its secretion.

2. Endocrine responses to insulin hypoglycaemia in the young calf.

3. Effects of glucagon on activities of hepatic enzymes in sheep.

4. Glucagon radioimmunoassay using antiserum 30K: interference by plasma.

5. Glucagon stimulation of gluconeogenesis from alanine in the intact dog.

6. Plasma glucagon concentrations in sheep: their regulation and relation to concentrations of insulin and growth hormone.

7. Separation of pancreatic and gut glucagon-like immunoreactivity (G.L.I.) with observations on plasma concentrations of these hormones during lactation.

8. Effect of blood glucose on glucagon secretion in anesthetized dogs.

9. Effect of glucagon on plasma alanine and glutamine metabolism and hepatic gluconeogenesis in sheep.

10. Effect of insulin-glucose infusions on plasma glucagon levels in fasting diabetics and nondiabetics.

1. Roles of glucagon and insulin in the regulation of metabolism in ruminants. A review.