W G Whitmore1, B J Curtin, D Fox. 1. Department of Ophthalmology, New York Hospital-Cornell University Medical Center, New York.
Abstract
PURPOSE: To study the effects of transcleral cryotherapy and laser photocoagulation of anterior retina on ocular growth. METHODS: Twenty-one rabbits underwent transcleral cryotherapy or indirect ophthalmoscopic laser photocoagulation of the anterior retina on one of their eyes between 2 and 8 weeks of age. RESULTS: After the rabbits were killed between 3 and 6 months of age, treated rabbit eyes were found to be significantly smaller in axial length (P < 0.001), average equatorial diameter (P < 0.01), average corneal diameter (P < 0.05), and in total ocular volume (P < 0.01). The difference in eye size was not due to lowered intraocular pressure. CONCLUSIONS: The results demonstrate that these treatments slow growth of both the anterior and posterior segment of rabbit eyes.
PURPOSE: To study the effects of transcleral cryotherapy and laser photocoagulation of anterior retina on ocular growth. METHODS: Twenty-one rabbits underwent transcleral cryotherapy or indirect ophthalmoscopic laser photocoagulation of the anterior retina on one of their eyes between 2 and 8 weeks of age. RESULTS: After the rabbits were killed between 3 and 6 months of age, treated rabbit eyes were found to be significantly smaller in axial length (P < 0.001), average equatorial diameter (P < 0.01), average corneal diameter (P < 0.05), and in total ocular volume (P < 0.01). The difference in eye size was not due to lowered intraocular pressure. CONCLUSIONS: The results demonstrate that these treatments slow growth of both the anterior and posterior segment of rabbit eyes.