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Literature DB >> 8321284

Molecular cloning of the olfactory neuronal transcription factor Olf-1 by genetic selection in yeast.

Abstract

A novel genetic selection in yeast has been used to isolate a complementary DNA for the transcriptional activator, Olf-1, which binds to the regulatory sequences of several olfactory-specific genes. The Olf-1 protein, expressed exclusively in the olfactory receptor neurons and their precursors, contains a new helix-loop-helix motif and functions as an apparent homodimer. Olf-1 may be the first member of a family of related proteins that may direct cellular differentiation in a variety of neuronal tissues.

Entities: Gene Species

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Year: 1993 PMID： 8321284 DOI： 10.1038/364121a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

129 in total

1. MYB-related transcription factor NtMYB2 induced by wounding and elicitors is a regulator of the tobacco retrotransposon Tto1 and defense-related genes.

Authors: K Sugimoto; S Takeda; H Hirochika
Journal: Plant Cell Date: 2000-12 Impact factor: 11.277

2. Protein kinase CK2alpha may induce gene expression but unlikely acts directly as a DNA-binding transcription-activating factor.

Authors: K Ackermann; W Pyerin
Journal: Mol Cell Biochem Date: 1999-01 Impact factor: 3.396

3. Rdp1, a novel zinc finger protein, regulates the DNA damage response of rhp51(+) from Schizosaccharomyces pombe.

Authors: Y S Shim; Y K Jang; M S Lim; J S Lee; R H Seong; S H Hong; S D Park
Journal: Mol Cell Biol Date: 2000-12 Impact factor: 4.272

4. LXRalpha functions as a cAMP-responsive transcriptional regulator of gene expression.

Authors: K Tamura; Y E Chen; M Horiuchi; Q Chen; L Daviet; Z Yang; M Lopez-Ilasaca; H Mu; R E Pratt; V J Dzau
Journal: Proc Natl Acad Sci U S A Date: 2000-07-18 Impact factor: 11.205

5. The clustered olfactory receptor gene family 262: genomic organization, promotor elements, and interacting transcription factors.

Authors: Reiner Hoppe; Henning Frank; Heinz Breer; Jörg Strotmann
Journal: Genome Res Date: 2003-12 Impact factor: 9.043

Review 6. The EBF/Olf/Collier family of transcription factors: regulators of differentiation in cells originating from all three embryonal germ layers.

Authors: David Liberg; Mikael Sigvardsson; Peter Akerblad
Journal: Mol Cell Biol Date: 2002-12 Impact factor: 4.272

Molecular cloning of the olfactory neuronal transcription factor Olf-1 by genetic selection in yeast.

1. MYB-related transcription factor NtMYB2 induced by wounding and elicitors is a regulator of the tobacco retrotransposon Tto1 and defense-related genes.

2. Protein kinase CK2alpha may induce gene expression but unlikely acts directly as a DNA-binding transcription-activating factor.

3. Rdp1, a novel zinc finger protein, regulates the DNA damage response of rhp51(+) from Schizosaccharomyces pombe.

4. LXRalpha functions as a cAMP-responsive transcriptional regulator of gene expression.

5. The clustered olfactory receptor gene family 262: genomic organization, promotor elements, and interacting transcription factors.

Review 6. The EBF/Olf/Collier family of transcription factors: regulators of differentiation in cells originating from all three embryonal germ layers.

7. Cloning of an olfactory sensory neuron-specific protein in the land snail (Eobania vermiculata).

Review 8. DNA-protein interactions: methods for detection and analysis.

9. Zfp423/OAZ mutation reveals the importance of Olf/EBF transcription activity in olfactory neuronal maturation.

10. Sir proteins, Rif proteins, and Cdc13p bind Saccharomyces telomeres in vivo.