Literature DB >> 8318716

In vitro tests of neurotoxicity.

E M Abdulla1, I C Campbell.   

Abstract

This review presents some of the newer techniques in the rapidly advancing area of neurotoxicity testing in vitro. They are not described at length, and more details can be obtained from the cited references. In vitro testing offers the possibility of relatively inexpensive screening of large numbers of pharmaceutical compounds, formulations, and environmental substances. The level of sophistication attained in this field may soon allow much more accurate safety limits to be set, as specific mechanisms of neurotoxicity are elucidated.

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Year:  1993        PMID: 8318716     DOI: 10.1016/1056-8719(93)90053-h

Source DB:  PubMed          Journal:  J Pharmacol Toxicol Methods        ISSN: 1056-8719            Impact factor:   1.950


  3 in total

1.  ASIC1a-specific modulation of acid-sensing ion channels in mouse cortical neurons by redox reagents.

Authors:  Xiang-Ping Chu; Natasha Close; Julie A Saugstad; Zhi-Gang Xiong
Journal:  J Neurosci       Date:  2006-05-17       Impact factor: 6.167

2.  13th Meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): alternative testing methodologies for organ toxicity.

Authors:  H Spielmann; N P Bochkov; L Costa; L Gribaldo; A Guillouzo; J J Heindel; M Karol; R Parchment; W Pfaller; P P Peraita; T Zacharewski
Journal:  Environ Health Perspect       Date:  1998-04       Impact factor: 9.031

3.  Neurotoxicity testing: a discussion of in vitro alternatives.

Authors:  L G Costa
Journal:  Environ Health Perspect       Date:  1998-04       Impact factor: 9.031

  3 in total

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