| Literature DB >> 8318540 |
Abstract
A bovine interferon alpha receptor (BoIFN-alpha R1) cDNA, homologous to the human cDNA, was isolated. Transfection of the BoIFN-alpha R1 cDNA into monkey COS cells results in a large increase in high-affinity binding sites for human IFN-alpha A and IFN-alpha B. Covalent crosslinking of radiolabeled HuIFN-alpha A and -alpha B demonstrates that the complex of [32P]HuIFN with the BoIFN-alpha R1 protein (predicted mass, 61,375) expressed in COS cells migrates as a 140-150 kDa band.Entities:
Mesh:
Substances:
Year: 1993 PMID: 8318540 DOI: 10.1016/0167-4781(93)90129-2
Source DB: PubMed Journal: Biochim Biophys Acta ISSN: 0006-3002