Literature DB >> 8316234

Purification and characterization of collagens from rat fibrosarcoma induced by 3-methylcholanthrene.

R Asokan1, R Puvanakrishnan, L V Ravichandran, V Kokila, G K Reddy, S C Dhar.   

Abstract

The distribution of various collagen types was studied in rat fibrosarcoma. Collagens extracted from fibrosarcoma tissue were characterized by the criteria of solubility in NaCl, SDS-PAGE, ion exchange chromatography, CNBr peptide mapping and amino acid analysis. Fibrosarcoma was found to produce excess amount of type V, type I trimer and type III collagens; comparatively, type I collagen and total collagen content were noticed to decrease in fibrosarcoma. We observe that the increase in type V collagen content in fibrosarcoma might be due to the enhanced transcription of type V collagen gene. Increased type I trimer collagen in fibrosarcoma might be attributed to the differential expression of alpha 1(I) and alpha 2(I) gene and might also be due to the expression of a different gene for type I trimer collagen.

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Year:  1993        PMID： 8316234     DOI： 10.1007/bf00925968

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  33 in total

1.  Suppression of synthesis of pro-alpha 1(I) and production of altered pro-alpha 2(I) procollagen subunits in 4-nitroquinoline-1-oxide-transformed fibroblasts.

Authors:  B Peterkofsky; W Prather
Journal:  J Biol Chem       Date:  1986-12-25       Impact factor: 5.157

2.  Collagen synthesis by short-term explants of pediatric tumors.

Authors:  Y A DeClerck; E Bogenmann; P A Jones
Journal:  Cancer Res       Date:  1985-03       Impact factor: 12.701

3.  A rapid method for the production of fibrosarcoma in rats and the effect of BCG administration.

Authors:  B Nagarajan; S Sankaran
Journal:  Indian J Cancer       Date:  1973-03       Impact factor: 1.224

4.  Systems for polyacrylamide gel electrophoresis.

Authors:  P J Blackshear
Journal:  Methods Enzymol       Date:  1984       Impact factor: 1.600

5.  Transcriptional control of human diploid fibroblast collagen synthesis by gamma-interferon.

Authors:  J Rosenbloom; G Feldman; B Freundlich; S A Jimenez
Journal:  Biochem Biophys Res Commun       Date:  1984-08-30       Impact factor: 3.575

6.  The molecular defect in a nonlethal variant of osteogenesis imperfecta. Synthesis of pro-alpha 2(I) chains which are not incorporated into trimers of type I procollagen.

Authors:  S B Deak; A Nicholls; F M Pope; D J Prockop
Journal:  J Biol Chem       Date:  1983-12-25       Impact factor: 5.157

7.  Synthesis of type V collagen by fibroblasts derived from normal, inflamed and hyperplastic human connective tissues.

Authors:  A S Narayanan; R C Page
Journal:  Coll Relat Res       Date:  1985-09

8.  Increased content of Type V Collagen in desmoplasia of human breast carcinoma.

Authors:  S H Barsky; C N Rao; G R Grotendorst; L A Liotta
Journal:  Am J Pathol       Date:  1982-09       Impact factor: 4.307

9.  Introduction of the human pro alpha 1(I) collagen gene into pro alpha 1(I)-deficient Mov-13 mouse cells leads to formation of functional mouse-human hybrid type I collagen.

Authors:  A Schnieke; M Dziadek; J Bateman; T Mascara; K Harbers; R Gelinas; R Jaenisch
Journal:  Proc Natl Acad Sci U S A       Date:  1987-02       Impact factor: 11.205

10.  Ultrastructural localization of type V collagen in rat kidney.

Authors:  A Martinez-Hernandez; S Gay; E J Miller
Journal:  J Cell Biol       Date:  1982-02       Impact factor: 10.539
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  5 in total

1.  Conformational dynamics accompanying the proteolytic degradation of trimeric collagen I by collagenases.

Authors:  Arjun S Adhikari; Emerson Glassey; Alexander R Dunn
Journal:  J Am Chem Soc       Date:  2012-08-01       Impact factor: 15.419

2.  The interface between catalytic and hemopexin domains in matrix metalloproteinase-1 conceals a collagen binding exosite.

Authors:  Laurence H Arnold; Louise E Butt; Stephen H Prior; Christopher M Read; Gregg B Fields; Andrew R Pickford
Journal:  J Biol Chem       Date:  2011-10-26       Impact factor: 5.157

3.  Carcinomas contain a matrix metalloproteinase-resistant isoform of type I collagen exerting selective support to invasion.

Authors:  Elena Makareeva; Sejin Han; Juan Carlos Vera; Dan L Sackett; Kenn Holmbeck; Charlotte L Phillips; Robert Visse; Hideaki Nagase; Sergey Leikin
Journal:  Cancer Res       Date:  2010-05-11       Impact factor: 12.701

4.  Molecular mechanism of type I collagen homotrimer resistance to mammalian collagenases.

Authors:  Sejin Han; Elena Makareeva; Natalia V Kuznetsova; Angela M DeRidder; Mary Beth Sutter; Wolfgang Losert; Charlotte L Phillips; Robert Visse; Hideaki Nagase; Sergey Leikin
Journal:  J Biol Chem       Date:  2010-05-12       Impact factor: 5.157

5.  Extracellular matrix components in uterine leiomyoma and their alteration during the tumour growth.

Authors:  M Wolańska; K Sobolewski; M Drozdzewicz; E Bańkowski
Journal:  Mol Cell Biochem       Date:  1998-12       Impact factor: 3.396
  5 in total

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