Literature DB >> 8315008

Differentiation between mouse-virulent and -avirulent strains of Toxoplasma gondii by a monoclonal antibody recognizing a 27-kilodalton antigen.

W Bohne1, U Gross, J Heesemann.   

Abstract

Using a murine monoclonal antibody, we were able to differentiate between mouse-virulent and -avirulent strains of Toxoplasma gondii. Monoclonal antibody TB6G5 was reactive with eight clinical mouse-avirulent isolates but not with mouse-virulent laboratory strains RH and BK. The antibody-reactive antigen was identified by indirect immunofluorescence and immunoblot as a 27-kDa cytoplasmic protein expressed by tachyzoites as well as by bradyzoites.

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Year:  1993        PMID: 8315008      PMCID: PMC265596          DOI: 10.1128/jcm.31.6.1641-1643.1993

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  18 in total

1.  Toxoplasma gondii: characterization and localization of antigens secreted from tachyzoites.

Authors:  H Charif; F Darcy; G Torpier; M F Cesbron-Delauw; A Capron
Journal:  Exp Parasitol       Date:  1990-07       Impact factor: 2.011

2.  Western blot analysis of the antibody response of patients with AIDS and toxoplasma encephalitis: antigenic diversity among Toxoplasma strains.

Authors:  L M Weiss; S A Udem; H Tanowitz; M Wittner
Journal:  J Infect Dis       Date:  1988-01       Impact factor: 5.226

3.  Isoenzymic characterization of seven strains of Toxoplasma gondii by isoelectrofocusing in polyacrylamide gels.

Authors:  M L Darde; B Bouteille; M Pestre-Alexandre
Journal:  Am J Trop Med Hyg       Date:  1988-12       Impact factor: 2.345

4.  Differences in virulence and development of encephalitis during chronic infection vary with the strain of Toxoplasma gondii.

Authors:  Y Suzuki; F K Conley; J S Remington
Journal:  J Infect Dis       Date:  1989-04       Impact factor: 5.226

5.  Isoenzyme studies on Toxoplasma gondii isolates using isoelectric focusing.

Authors:  G Barnert; A Hassl; H Aspöck
Journal:  Zentralbl Bakteriol Mikrobiol Hyg A       Date:  1988-06

Review 6.  The antigenic structure of Toxoplasma gondii: a review.

Authors:  A M Johnson
Journal:  Pathology       Date:  1985-01       Impact factor: 5.306

7.  Comparison of the development of avirulent and virulent strains of Toxoplasma gondii in the peritoneal exudate of mice.

Authors:  D J Ferguson; W M Hutchison
Journal:  Ann Trop Med Parasitol       Date:  1981-10

8.  Virulence of toxoplasma.

Authors:  H de Roever-Bonnet
Journal:  Trop Geogr Med       Date:  1966-06

9.  Strain-specific antigens of Toxoplasma gondii.

Authors:  P L Ware; L H Kasper
Journal:  Infect Immun       Date:  1987-03       Impact factor: 3.441

10.  Antibody responses to toxoplasma antigens in mice infected with strains of different virulence.

Authors:  E Handman; J S Remington
Journal:  Infect Immun       Date:  1980-07       Impact factor: 3.441

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  3 in total

1.  Microsatellite in the beta-tubulin gene of Toxoplasma gondii as a new genetic marker for use in direct screening of amniotic fluids.

Authors:  J M Costa; M L Dardé; B Assouline; M Vidaud; S Bretagne
Journal:  J Clin Microbiol       Date:  1997-10       Impact factor: 5.948

2.  rRNA gene sequence heterogeneity among Toxoplasma gondii strains.

Authors:  K Luton; M Gleeson; A M Johnson
Journal:  Parasitol Res       Date:  1995       Impact factor: 2.289

Review 3.  Importance of serological cross-reactivity among Toxoplasma gondii, Hammondia spp., Neospora spp., Sarcocystis spp. and Besnoitia besnoiti.

Authors:  Luís F P Gondim; José R Mineo; Gereon Schares
Journal:  Parasitology       Date:  2017-02-28       Impact factor: 3.234

  3 in total

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