Literature DB >> 8314681

Energy metabolism in muscle paresis and recovery studied by 31P-MR spectroscopy: a case report.

R Funicello1, B Barbiroli, P Zaniol, P Martinelli.   

Abstract

We report a 31P Magnetic Resonance Spectroscopy (31P-MRS) study on the changes of energy metabolism in human leg anterior and lateral compartment muscles with paresis due to compression from a herniated lumbar disc at the L4-L5 level and recovery to normality. A low phosphocreatine to inorganic phosphate ratio due to both decreased phosphocreatine and increased inorganic phosphate contents and a normal intracellular pH were the features of muscles with paresis. Changes of 31P-MRS parameters were followed during 18 weeks of treatment with physical therapy until complete recovery. Results show that 31P-MRS is a useful clinical tool for detecting even small biochemical changes that may occur in muscles and for checking the effects of therapy.

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Year:  1993        PMID： 8314681     DOI： 10.1007/bf02335669

Source DB:  PubMed          Journal:  Ital J Neurol Sci        ISSN： 0392-0461


  15 in total

1.  Abnormal brain and muscle energy metabolism shown by 31P magnetic resonance spectroscopy in patients affected by migraine with aura.

Authors:  B Barbiroli; P Montagna; P Cortelli; R Funicello; S Iotti; L Monari; G Pierangeli; P Zaniol; E Lugaresi
Journal:  Neurology       Date:  1992-06       Impact factor: 9.910

Review 2.  Applications of nuclear magnetic resonance spectroscopy in pathology.

Authors:  G K Radda; D J Taylor
Journal:  Int Rev Exp Pathol       Date:  1985

3.  Energy metabolism of the untrained muscle of elite runners as observed by 31P magnetic resonance spectroscopy: evidence suggesting a genetic endowment for endurance exercise.

Authors:  J H Park; R L Brown; C R Park; M Cohn; B Chance
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

4.  Applications of 31P NMR to clinical biochemistry.

Authors:  B Chance
Journal:  Ann N Y Acad Sci       Date:  1984       Impact factor: 5.691

5.  31P-NMR spectroscopy of skeletal muscle in Becker dystrophy and DMD/BMD carriers. Altered rate of phosphate transport.

Authors:  B Barbiroli; R Funicello; S Iotti; P Montagna; A Ferlini; P Zaniol
Journal:  J Neurol Sci       Date:  1992-06       Impact factor: 3.181

6.  Metabolic changes in human muscle denervation: topical 31P NMR spectroscopy studies.

Authors:  D W Zochodne; R T Thompson; A A Driedger; M J Strong; D Gravelle; C F Bolton
Journal:  Magn Reson Med       Date:  1988-08       Impact factor: 4.668

7.  Multiple controls of oxidative metabolism in living tissues as studied by phosphorus magnetic resonance.

Authors:  B Chance; J S Leigh; J Kent; K McCully; S Nioka; B J Clark; J M Maris; T Graham
Journal:  Proc Natl Acad Sci U S A       Date:  1986-12       Impact factor: 11.205

8.  Cerebral metabolism in hyper- and hypocarbia: 31P and 1H nuclear magnetic resonance studies.

Authors:  O A Petroff; J W Prichard; K L Behar; D L Rothman; J R Alger; R G Shulman
Journal:  Neurology       Date:  1985-12       Impact factor: 9.910

9.  Phosphorus NMR spectroscopy study of muscular enzyme deficiencies involving glycogenolysis and glycolysis.

Authors:  D Duboc; P Jehenson; S Tran Dinh; C Marsac; A Syrota; M Fardeau
Journal:  Neurology       Date:  1987-04       Impact factor: 9.910

10.  Investigation of human mitochondrial myopathies by phosphorus magnetic resonance spectroscopy.

Authors:  D L Arnold; D J Taylor; G K Radda
Journal:  Ann Neurol       Date:  1985-08       Impact factor: 10.422
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