| Literature DB >> 8314590 |
C B Cleutjens1, C C van Eekelen, H van Dekken, E M Smit, A Hagemeijer, M J Wagner, D E Wells, J Trapman.
Abstract
In an attempt to identify C/EBP-like transcription factors expressed in the prostate, a cDNA homologous to the mouse C/EBP delta (CRP3) and the rat CELF gene was isolated. A genomic clone containing the entire C/EBP delta gene was isolated using a cDNA fragment as a probe. The gene was characterized by restriction mapping and sequence analysis. By fluorescence in situ hybridization, using the biotinylated genomic clone as a probe, the C/EBP delta gene was assigned to the pericentromeric region of human chromosome 8, most probably to 8q11. This chromosomal localization was confirmed by analysis of a panel of human x hamster somatic cell hybrid DNA samples with a C/EBP delta-specific STS. As a result, the C/EBP delta gene could be positioned between the PLAT and the MOS loci.Entities:
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Year: 1993 PMID： 8314590 DOI： 10.1006/geno.1993.1220
Source DB: PubMed Journal: Genomics ISSN： 0888-7543 Impact factor: 5.736