Literature DB >> 8314586

The CEPH consortium linkage map of human chromosome 13.

A M Bowcock1, S C Gerken, R I Barnes, R Shiang, E W Jabs, A C Warren, S Antonarakis, A E Retief, G Vergnaud, M Leppert.   

Abstract

The CEPH consortium map of chromosome 13 is presented. This map contains 59 loci defined by genotypes generated from CEPH family DNAs with 94 different probe and restriction enzyme combinations contributed by 9 laboratories. A total of 25 loci have been placed on the map with likelihood support of at least 1000:1. The map extends from loci in the centromeric region of chromosome 13 to the terminal band of the long arm. Multipoint linkage analyses provided estimates that the male, female, and sex-averaged maps extend for 158, 203, and 178 cM respectively. The largest interval is 24 cM and is between D13Z1 (alpha RI) and ATP1AL1. The mean genetic distance between the 25 uniquely placed loci is 7 cM.

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Year:  1993        PMID: 8314586     DOI: 10.1006/geno.1993.1215

Source DB:  PubMed          Journal:  Genomics        ISSN: 0888-7543            Impact factor:   5.736


  1 in total

1.  Breakpoint analysis: precise localization of genetic markers by means of nonstatistical computation using relatively few genotypes.

Authors:  T I Elsner; H Albertsen; S C Gerken; P Cartwright; R White
Journal:  Am J Hum Genet       Date:  1995-02       Impact factor: 11.025

  1 in total

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