| Literature DB >> 8314484 |
V Di Marco1, O Lo Iacono, M Capra, S Grutta, C Ciaccio, C Gerardi, A Maggio, D Renda, P Almasio, R Pisa.
Abstract
In this open, pilot study, interferon (IFN) alpha-2b seemed effective in the treatment of hepatitis C virus (HCV) infection in patients with beta-thalassaemia. In seven of nine patients who completed the study alanine aminotransferase activities returned to normal, and a completely stable response 24 months after treatment was seen in five. Liver biopsy specimen showed a clear reduction in portal, periportal, and lobular necroinflammation in all five cases. Three patients stopped treatment early because of side effects.Entities:
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Year: 1993 PMID： 8314484 PMCID： PMC1374044 DOI： 10.1136/gut.34.2_suppl.s142
Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059