Literature DB >> 831284

Suppression of the temperature-sensitive phenotype of a mutant of reovirus type 3.

R F Ramig, R M White, B N Fields.   

Abstract

A revertant of a reovirus group A temperature-sensitive mutant was crossed with wild type. More than 50 percent of the progeny were temperature sensitive. In all of the temperature-sensitive progeny examined by recombination tests, the temperature-sensitive lesion was in group A. The results indicate that the revertant was phenotypically suppressed.

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Year:  1977        PMID： 831284     DOI： 10.1126/science.831284

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  7 in total

1.  Monoclonal antibodies to reovirus reveal structure/function relationships between capsid proteins and genetics of susceptibility to antibody action.

Authors:  H W Virgin; M A Mann; B N Fields; K L Tyler
Journal:  J Virol       Date:  1991-12       Impact factor: 5.103

2.  Persistent infections in L cells with temperature-sensitive mutants of reovirus.

Authors:  R Ahmed; A F Graham
Journal:  J Virol       Date:  1977-08       Impact factor: 5.103

3.  Genetic mapping of reovirus virulence and organ tropism in severe combined immunodeficient mice: organ-specific virulence genes.

Authors:  B L Haller; M L Barkon; G P Vogler; H W Virgin
Journal:  J Virol       Date:  1995-01       Impact factor: 5.103

Review 4.  Structure and function of the reovirus genome.

Authors:  W K Joklik
Journal:  Microbiol Rev       Date:  1981-12

5.  Genetic variation during persistent reovirus infection: presence of extragenically suppressed temperature-sensitive lesions in wild-type virus isolated from persistently infected L cells.

Authors:  R Ahmed; P R Chakraborty; A F Graham; R F Ramig; B N Fields
Journal:  J Virol       Date:  1980-05       Impact factor: 5.103

6.  Transcription of methylated viral DNA by eukaryotic RNA polymerase II.

Authors:  D B Willis; J P Thompson; K Essani; R Goorha
Journal:  Cell Biophys       Date:  1989 Aug-Oct

7.  Temperature-sensitive mutants of influenza A virus. Transfer of the two ts-1A2 ts lesions present in the Udorn/72-ts-1A2 donor virus to the influenza A/Alaska/6/77 (H3N2) wild type virus.

Authors:  B R Murphy; F T Wood; J G Massicot; R M Chanock
Journal:  Arch Virol       Date:  1980       Impact factor: 2.574
  7 in total

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