Literature DB >> 831257

Thymic muscle cells bear acetylcholine receptors: possible relation to myasthenia gravis.

I Kao, D B Drachman.   

Abstract

Culture of dissociated thymus from rats and humans yielded cells identical to skeletal muscle with respect to morphology, contractility, electrophysiological properties, and the presence of acetylcholine receptors. These cells, strategically located in the thymus, may play a role in initiation of the autoimmune response against acetylcholine receptors, which is characteristic of myasthenia gravis.

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Year:  1977        PMID： 831257     DOI： 10.1126/science.831257

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  39 in total

Review 1.  Intrathymic expression of neuromuscular acetylcholine receptors and the immunpathogenesis of myasthenia gravis.

Authors:  Arnold I Levinson; Yi Zheng; Glen Gaulton; Decheng Song; Jonni Moore; C Hank Pletcher
Journal:  Immunol Res       Date:  2003       Impact factor: 2.829

2.  Histochemical and ultrastructural properties of myoid cells in the thymus of the frog.

Authors:  V Hanzliková
Journal:  Cell Tissue Res       Date:  1979-03-09       Impact factor: 5.249

3.  Nicotinic acetylcholine receptor expression on B-lymphoblasts of healthy versus schizophrenic subjects stratified for smoking: [3H]-nicotine binding is decreased in schizophrenia and correlates with negative symptoms.

Authors:  Christian Luckhaus; Uwe Henning; Stefano Ferrea; Francesco Musso; Arian Mobascher; Georg Winterer
Journal:  J Neural Transm (Vienna)       Date:  2011-12-11       Impact factor: 3.575

Review 4.  Desensitization of the nicotinic acetylcholine receptor: molecular mechanisms and effect of modulators.

Authors:  E L Ochoa; A Chattopadhyay; M G McNamee
Journal:  Cell Mol Neurobiol       Date:  1989-06       Impact factor: 5.046

5.  Granzyme B: evidence for a role in the origin of myasthenia gravis.

Authors:  L Casciola-Rosen; A Miagkov; K Nagaraju; F Askin; L Jacobson; A Rosen; D B Drachman
Journal:  J Neuroimmunol       Date:  2008-08-03       Impact factor: 3.478

6.  Association of nerve fibres with myoid cells in the chick thymus.

Authors:  A S Chan
Journal:  J Anat       Date:  1992-12       Impact factor: 2.610

Review 7.  Myasthenia gravis: an autoimmune response against the acetylcholine receptor.

Authors:  Y M Graus; M H De Baets
Journal:  Immunol Res       Date:  1993       Impact factor: 2.829

Review 8.  Immunopathogenesis and treatment of myasthenia gravis.

Authors:  A I Levinson; B Zweiman; R P Lisak
Journal:  J Clin Immunol       Date:  1987-05       Impact factor: 8.317

Review 9.  Thymectomy in myasthenia gravis. A review.

Authors:  H J Oosterhuis
Journal:  Ital J Neurol Sci       Date:  1983-12

10.  Intrathymic lymphoid cell differentiation in myasthenia gravis: an immunophenotypic study.

Authors:  M F Ferrio; L Durelli; U Massazza; R Cavallo; G Poccardi; G Maggi; C Casadio; M Di Summa; L Bergamini
Journal:  Ital J Neurol Sci       Date:  1991-12
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