Literature DB >> 8310537

Thinking about genetic redundancy.

J H Thomas1.   

Abstract

Partial functional redundancy among genes is frequently observed in a wide range of organisms and processes, but the selective value of such redundancy is not immediately apparent. Any fully redundant function should be evolutionarily unstable: unless selection acts to maintain the redundancy it will tend to be lost by mutational drift. I discuss four possible mechanisms by which selection might act to maintain genetic redundancy.

Mesh:

Year:  1993        PMID: 8310537     DOI: 10.1016/0168-9525(93)90140-d

Source DB:  PubMed          Journal:  Trends Genet        ISSN: 0168-9525            Impact factor:   11.639


  73 in total

1.  Annealing of RNA editing substrates facilitated by guide RNA-binding protein gBP21.

Authors:  U F Müller; L Lambert; H U Göringer
Journal:  EMBO J       Date:  2001-03-15       Impact factor: 11.598

Review 2.  Advanced transgenic and gene-targeting approaches.

Authors:  X Gao; A Kemper; B Popko
Journal:  Neurochem Res       Date:  1999-09       Impact factor: 3.996

3.  The Arabidopsis locus RCB mediates upstream regulation of mitotic gene expression.

Authors:  Kristiina Himanen; Christophe Reuzeau; Tom Beeckman; Siegbert Melzer; Olivier Grandjean; Liz Corben; Dirk Inze
Journal:  Plant Physiol       Date:  2003-12       Impact factor: 8.340

4.  Transcriptional regulation: a genomic overview.

Authors:  José Luis Riechmann
Journal:  Arabidopsis Book       Date:  2002-04-04

5.  Role of negative regulation in promoter specificity of the homologous transcriptional activators Ace2p and Swi5p.

Authors:  P R Dohrmann; W P Voth; D J Stillman
Journal:  Mol Cell Biol       Date:  1996-04       Impact factor: 4.272

Review 6.  A genetic approach to dissect sexually dimorphic behaviors.

Authors:  Scott A Juntti; Jennifer K Coats; Nirao M Shah
Journal:  Horm Behav       Date:  2008-01-05       Impact factor: 3.587

7.  Detection of subtle phenotypes: the case of the cell adhesion molecule csA in Dictyostelium.

Authors:  E Ponte; E Bracco; J Faix; S Bozzaro
Journal:  Proc Natl Acad Sci U S A       Date:  1998-08-04       Impact factor: 11.205

8.  The identities of sym-2, sym-3 and sym-4, three genes that are synthetically lethal with mec-8 in Caenorhabditis elegans.

Authors:  John Yochem; Leslie R Bell; Robert K Herman
Journal:  Genetics       Date:  2004-11       Impact factor: 4.562

9.  SPT10 and SPT21 are required for transcription of particular histone genes in Saccharomyces cerevisiae.

Authors:  C Dollard; S L Ricupero-Hovasse; G Natsoulis; J D Boeke; F Winston
Journal:  Mol Cell Biol       Date:  1994-08       Impact factor: 4.272

10.  Genetic interactions between the Drosophila Abelson (Abl) tyrosine kinase and failed axon connections (fax), a novel protein in axon bundles.

Authors:  K K Hill; V Bedian; J L Juang; F M Hoffmann
Journal:  Genetics       Date:  1995-10       Impact factor: 4.562

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.