Literature DB >> 8309955

A nonferrous instrumental joystick device for recording behavioral responses during magnetic resonance imaging and spectroscopy.

S E Lukas1, M Dobrosielski, T M Chiu, B T Woods, S K Teoh, J H Mendelson.   

Abstract

A nonferrous joystick device was developed to permit subjects to continuously report ethanol-induced alterations in subjective mood states while undergoing a magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) procedure. The device utilizes air pressure (supplied by a small compressor) that is directed to a series of tubes that terminate in a hand-held unit. The hand-held unit easily fits inside the magnet and resembles a standard computer game joystick except that the ends of the air hoses replace the buttons. The control unit contains three pressure transducers, which are triggered when the tubes are occluded by the subject, activating different pens on an event marker located 6 m from the whole body imager. The unit is safe to use inside a 1.5-Tesla magnetic field and does not disrupt the MRI and MRS recording procedures. Subjective reports of ethanol-induced euphoria and intoxication paralleled the MRS detection of ethanol in the brain. This device could prove to be useful in numerous behavioral studies involving whole-body MRI and MRS.

Entities:  

Mesh:

Substances:

Year:  1993        PMID: 8309955     DOI: 10.1016/0091-3057(93)90201-4

Source DB:  PubMed          Journal:  Pharmacol Biochem Behav        ISSN: 0091-3057            Impact factor:   3.533


  2 in total

1.  An MR-compatible device for delivering smoked marijuana during functional imaging.

Authors:  Blaise deB Frederick; Kimberly P Lindsey; Lisa D Nickerson; Elizabeth T Ryan; Scott E Lukas
Journal:  Pharmacol Biochem Behav       Date:  2007-04-13       Impact factor: 3.533

2.  Sex differences in plasma cocaine levels and subjective effects after acute cocaine administration in human volunteers.

Authors:  S E Lukas; M Sholar; L H Lundahl; X Lamas; E Kouri; J D Wines; L Kragie; J H Mendelson
Journal:  Psychopharmacology (Berl)       Date:  1996-06       Impact factor: 4.530

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.