Literature DB >> 8308857

The discovery of sulfonamide endothelin antagonists and the development of the orally active ETA antagonist 5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulf onamide.

P D Stein1, J T Hunt, D M Floyd, S Moreland, K E Dickinson, C Mitchell, E C Liu, M L Webb, N Murugesan, J Dickey.   

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Year:  1994        PMID： 8308857     DOI： 10.1021/jm00029a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  7 in total

1.  Liquid-phase combinatorial synthesis.

Authors:  H Han; M M Wolfe; S Brenner; K D Janda
Journal:  Proc Natl Acad Sci U S A       Date:  1995-07-03       Impact factor: 11.205

Review 2.  Emerging drugs for preeclampsia--the endothelium as a target.

Authors:  Jennifer M Sasser; Sydney R Murphy; Joey P Granger
Journal:  Expert Opin Emerg Drugs       Date:  2015-07-03       Impact factor: 4.191

3.  Systemic hypertension induced by hepatic overexpression of human preproendothelin-1 in rats.

Authors:  V Niranjan; S Télémaque; D deWit; R D Gerard; M Yanagisawa
Journal:  J Clin Invest       Date:  1996-11-15       Impact factor: 14.808

4.  Selective blockade of the endothelin subtype A receptor decreases early atherosclerosis in hamsters fed cholesterol.

Authors:  M C Kowala; P M Rose; P D Stein; N Goller; R Recce; S Beyer; M Valentine; D Barton; S K Durham
Journal:  Am J Pathol       Date:  1995-04       Impact factor: 4.307

5.  Characterization of three non-peptide endothelin receptor ligands using human cloned ETA and ETB receptors.

Authors:  K W Buchan; C Alldus; C Christodoulou; K L Clark; C W Dykes; M J Sumner; D M Wallace; D G White; I S Watts
Journal:  Br J Pharmacol       Date:  1994-08       Impact factor: 8.739

6.  Characterization of endothelin receptors in rat renal artery in vitro.

Authors:  K L Clark; L Pierre
Journal:  Br J Pharmacol       Date:  1995-02       Impact factor: 8.739

7.  Role of endothelin-1 and the ETA receptor in the maintenance of deoxycorticosterone acetate-salt-induced hypertension.

Authors:  K Fujita; Y Matsumura; S Kita; Y Miyazaki; K Hisaki; M Takaoka; S Morimoto
Journal:  Br J Pharmacol       Date:  1995-03       Impact factor: 8.739
  7 in total

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