| Literature DB >> 830822 |
K R Hetzel, B R Westerman, J L Quinn, S Meyers, V Barresi.
Abstract
Sodium bicarbonate was used to enhance the myocardial concentration of Tl-201 in rabbits and dogs. Organ distribution studies in rabbits and in vivo imaging in dogs showed a 1.5-2 fold increase in myocardial Tl-201 concentration in bicarbonate-treated animals as compared with matched controls. Image improvement was noted, with threefold enhancement of myocardium-to-liver ratios. The results suggest that a similar improvement may be possible for clinical myocardial imaging.Entities:
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Year: 1977 PMID: 830822
Source DB: PubMed Journal: J Nucl Med ISSN: 0161-5505 Impact factor: 10.057