Literature DB >> 8307783

New major histocompatibility complex genes.

B Marshall1, C Leelayuwat, M A Degli-Esposti, M Pinelli, L J Abraham, R L Dawkins.   

Abstract

The MHC is a region of some 4 megabases that has been studied intensively owing to the large number of diseases that are associated with susceptibility genes within this region of the genome. The total number of genes located within the MHC is now approximately 100, but more can be predicted. Recently identified genes within the MHC include PERB6, a large gene producing multiple transcripts located between HLA-B and TNF, and PERB1, a member of the protein tyrosine kinase-gene family. PERB6 was identified by YAC probing of tissue blots, while PERB1 was identified by genomic sequencing.

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Year:  1993        PMID： 8307783     DOI： 10.1016/0198-8859(93)90516-4

Source DB:  PubMed          Journal:  Hum Immunol        ISSN： 0198-8859            Impact factor:   2.850


  7 in total

1.  SNP profile within the human major histocompatibility complex reveals an extreme and interrupted level of nucleotide diversity.

Authors:  S Gaudieri; R L Dawkins; K Habara; J K Kulski; T Gojobori
Journal:  Genome Res       Date:  2000-10       Impact factor: 9.043

2.  Role of major histocompatibility complex class I-related molecules A*A5.1 allele in ulcerative colitis in Chinese patients.

Authors:  Min Lü; Bing Xia; Liuqing Ge; Yi Li; Jie Zhao; Fan Chen; Feng Zhou; Xiaolian Zhang; Jinquan Tan
Journal:  Immunology       Date:  2008-11-07       Impact factor: 7.397

3.  The major histocompatability complex (MHC) contains conserved polymorphic genomic sequences that are shuffled by recombination to form ethnic-specific haplotypes.

Authors:  S Gaudieri; C Leelayuwat; G K Tay; D C Townend; R L Dawkins
Journal:  J Mol Evol       Date:  1997-07       Impact factor: 2.395

4.  Strong association between microsatellites and an HLA-B, DR haplotype (B18-DR3): implication for microsatellite evolution.

Authors:  B Crouau-Roy; N Bouzekri; C Carcassi; J Clayton; L Contu; A Cambon-Thomsen
Journal:  Immunogenetics       Date:  1996       Impact factor: 2.846

5.  Genomic characterization of the region between HLA-B and TNF: implications for the evolution of multicopy gene families.

Authors:  S Gaudieri; C Leelayuwat; D C Townend; J K Kulski; R L Dawkins
Journal:  J Mol Evol       Date:  1997       Impact factor: 2.395

6.  Linkage analysis of human leukocyte antigen (HLA) markers in familial psoriasis: strong disequilibrium effects provide evidence for a major determinant in the HLA-B/-C region.

Authors:  S Jenisch; T Henseler; R P Nair; S W Guo; E Westphal; P Stuart; M Krönke; J J Voorhees; E Christophers; J T Elder
Journal:  Am J Hum Genet       Date:  1998-07       Impact factor: 11.025

7.  Quality assessment parameters for EST-derived SNPs from catfish.

Authors:  Shaolin Wang; Zhenxia Sha; Tad S Sonstegard; Hong Liu; Peng Xu; Benjaporn Somridhivej; Eric Peatman; Huseyin Kucuktas; Zhanjiang Liu
Journal:  BMC Genomics       Date:  2008-09-30       Impact factor: 3.969
  7 in total

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