| Literature DB >> 8306788 |
B Crestani1, A Jaccard, D Israël-Biet, L J Couderc, J Frija, J P Clauvel.
Abstract
A patient developed an interstitial pneumonitis while receiving chlorambucil for a chronic lymphocytic leukemia (cumulative dose, 8,340 mg). Withdrawal of drug treatment was followed by rapid improvement in the clinical condition. Bronchoalveolar lavage showed a T-lymphocytic alveolitis, whereas blood lymphocytes were predominantly of the B phenotype. The T-lymphocytic alveolitis persisted 6 weeks after drug therapy cessation with a predominant CD8+ phenotype, as observed in some hypersensitivity pneumonitis induced by drugs.Entities:
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Year: 1994 PMID： 8306788 DOI： 10.1378/chest.105.2.634
Source DB: PubMed Journal: Chest ISSN： 0012-3692 Impact factor: 9.410