Literature DB >> 8305132

How alpha beta T-cell receptors 'see' peptide/MHC complexes.

Y H Chien1, M M Davis.   

Abstract

Recent results have added new information to our understanding of alpha beta T-cell receptor mediated recognition. In particular, we find that the V(D)J junction or 'CDR3' portion of TCR alpha and beta seem most important in contacting peptides bound to MHC molecules, consistent with previous predictions. Surprisingly, these same CDR3-peptide contacts also appear to have a major influence on the TCR-MHC molecule interactions as well.

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Year:  1993        PMID： 8305132     DOI： 10.1016/0167-5699(93)90199-u

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  24 in total

1.  Role of intramembrane charged residues in the quality control of unassembled T-cell receptor alpha-chains at the endoplasmic reticulum.

Authors:  Nia Soetandyo; Qiuyan Wang; Yihong Ye; Lianyun Li
Journal:  J Cell Sci       Date:  2010-04-01       Impact factor: 5.285

2.  Covalent assembly of a soluble T cell receptor-peptide-major histocompatibility class I complex.

Authors:  C Grégoire; S Y Lin; G Mazza; N Rebai; I F Luescher; B Malissen
Journal:  Proc Natl Acad Sci U S A       Date:  1996-07-09       Impact factor: 11.205

Review 3.  CD8+ effector T cells at the fetal-maternal interface, balancing fetal tolerance and antiviral immunity.

Authors:  Tamara Tilburgs; Jack L Strominger
Journal:  Am J Reprod Immunol       Date:  2013-02-23       Impact factor: 3.886

Review 4.  Conformational changes in MHC class I molecules. Antibody, T-cell receptor, and NK cell recognition in an HLA-B7 model system.

Authors:  K D Smith; Z B Kurago; C T Lutz
Journal:  Immunol Res       Date:  1997       Impact factor: 2.829

5.  Restrictions of T cell receptor beta chain repertoire in the peripheral blood of patients with systemic lupus erythematosus.

Authors:  M R Holbrook; P J Tighe; R J Powell
Journal:  Ann Rheum Dis       Date:  1996-09       Impact factor: 19.103

Review 6.  Antibodies to CD45 and other cell membrane antigens in systemic lupus erythematosus.

Authors:  J B Winfield; P Fernsten; J Czyzyk; E Wang; J Marchalonis
Journal:  Springer Semin Immunopathol       Date:  1994

7.  Different levels of T-cell receptor triggering induce distinct functions in hepatitis B and hepatitis C virus-specific human CD4(+) T-cell clones.

Authors:  H M Diepolder; N H Gruener; J T Gerlach; M C Jung; E A Wierenga; G R Pape
Journal:  J Virol       Date:  2001-09       Impact factor: 5.103

8.  Non-fastidious, melanoma-specific CD8+ cytotoxic T lymphocytes from choroidal melanoma patients.

Authors:  X Q Huang; M S Mitchell; P E Liggett; A L Murphree; J Kan-Mitchell
Journal:  Cancer Immunol Immunother       Date:  1994-06       Impact factor: 6.968

Review 9.  The T cell receptor (TCR) in HLA-B27-restricted T cell responses--an introduction.

Authors:  E Märker-Hermann; R Duchmann; E May; B Ackermann; K H Meyer Zum Büschenfelde
Journal:  Clin Rheumatol       Date:  1996-01       Impact factor: 2.980

10.  Cross-reactive T-cell responses to the nonstructural regions of dengue viruses among dengue fever and dengue hemorrhagic fever patients in Malaysia.

Authors:  Ramapraba Appanna; Tan Lian Huat; Lucy Lum Chai See; Phoay Lay Tan; Jamuna Vadivelu; Shamala Devi
Journal:  Clin Vaccine Immunol       Date:  2007-06-13
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