Literature DB >> 830495

Sudden withdrawal of propranolol in patients with angina pectoris.

M G Myers, G Wisenberg.   

Abstract

On 51 of 53 occasions, sudden withdrawal of propranolol from patients with angina pectoris produced no substantial adverse effects. Two patients experienced a recurrence of unstable angina with one man sustaining a fatal myocardial infarction ten days after propranolol withdrawal. These observations suggest that patients with previous unstable angina may be dependent upon beta-adrenoceptor blockade. Sudden cessation of propranolol for short periods may be preferable to tapering the dosage if prolonged periods of sub-optimal beta-adrenoceptor blockade are to be avoided.

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Year:  1977        PMID： 830495     DOI： 10.1378/chest.71.1.24

Source DB:  PubMed          Journal:  Chest        ISSN： 0012-3692            Impact factor:   9.410


  6 in total

1.  Symptom-limited exercise combined with dipyridamole stress: prognostic value in assessment of known or suspected coronary artery disease by use of gated SPECT imaging.

Authors:  Alan W Ahlberg; Sarkis B Baghdasarian; Haris Athar; Jeffrey P Thompsen; Deborah M Katten; Gavin L Noble; Igor Mamkin; Anuj R Shah; Ivette A Leka; Gary V Heller
Journal:  J Nucl Cardiol       Date:  2008 Jan-Feb       Impact factor: 5.952

Review 2.  The syndrome associated with the withdrawal of beta-adrenergic receptor blocking drugs.

Authors:  B N Prichard; R J Walden
Journal:  Br J Clin Pharmacol       Date:  1982       Impact factor: 4.335

3.  The phenomenon of beta-adrenergic hypersensitivity following propranolol withdrawal studied in normal subjects.

Authors:  K S Kiyingi; J Shaw
Journal:  Eur J Clin Pharmacol       Date:  1984       Impact factor: 2.953

4.  Sudden versus gradual withdrawal of sotalol in ambulant patients with ischaemic heart disease.

Authors:  A Henderson; J Errington
Journal:  Br Heart J       Date:  1982-12

5.  Dobutamine stress MRI. Part I. Safety and feasibility of dobutamine cardiovascular magnetic resonance in patients suspected of myocardial ischemia.

Authors:  Dirkjan Kuijpers; Caroline H C Janssen; Paul R M van Dijkman; Matthijs Oudkerk
Journal:  Eur Radiol       Date:  2004-07-24       Impact factor: 5.315

Review 6.  Beta-blocker therapy and the risk of anaphylaxis.

Authors:  J H Toogood
Journal:  CMAJ       Date:  1987-05-01       Impact factor: 8.262
  6 in total

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