Literature DB >> 8304188

Quinazoline antifolates inhibiting thymidylate synthase: synthesis of gamma-linked peptide and amide analogues of 2-desamino-2-methyl-N10-propargyl- 5,8-dideazafolic acid (ICI 198583).

V Bavetsias1, A L Jackman, T J Thornton, K Pawelczak, F T Boyle, G M Bisset.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8304188     DOI： 10.1007/978-1-4615-2960-6_121

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


× No keyword cloud information.
  2 in total

1.  Comparison of plasma and tissue levels of ZD1694 (Tomudex), a highly polyglutamatable quinazoline thymidylate synthase inhibitor, in preclinical models.

Authors:  G W Aherne; E Ward; N Lawrence; D Dobinson; S J Clarke; H Musgrove; F Sutcliffe; T Stephens; A L Jackman
Journal:  Br J Cancer       Date:  1998       Impact factor: 7.640

2.  Mechanisms of acquired resistance to the quinazoline thymidylate synthase inhibitor ZD1694 (Tomudex) in one mouse and three human cell lines.

Authors:  A L Jackman; L R Kelland; R Kimbell; M Brown; W Gibson; G W Aherne; A Hardcastle; F T Boyle
Journal:  Br J Cancer       Date:  1995-05       Impact factor: 7.640
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.