Literature DB >> 8300537

The mannitol repressor (MtlR) of Escherichia coli.

R M Figge1, T M Ramseier, M H Saier.   

Abstract

The mannitol operon of Escherichia coli, encoding the mannitol-specific enzyme II of the phosphotransferase system (Mt1A) and mannitol phosphate dehydrogenase (Mt1D), is here shown to contain a single additional downstream open reading frame which encodes the mannitol repressor (Mt1R). Mt1R contains 195 amino acids and has a calculated molecular weight of 21,990 and a calculated pI of 4.5. It is homologous to the product of an open reading frame (URF2D) upstream of the E. coli gapB gene but represents a novel type of transcriptional regulatory protein.

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Year:  1994        PMID: 8300537      PMCID: PMC205122          DOI: 10.1128/jb.176.3.840-847.1994

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  53 in total

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7.  The mannitol operon repressor MtlR belongs to a new class of transcription regulators in bacteria.

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10.  The general PTS component HPr determines the preference for glucose over mannitol.

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