Literature DB >> 8299715

Production of interleukin-1 by primary cultured parenchymal liver cells (hepatocytes).

T Tsukui1, K Kikuchi, A Mabuchi, T Sudo, T Sakamoto, G Asano, K Yokomuro.   

Abstract

The production of interleukin-1 (IL-1) by cultured parenchymal liver cells was revealed by a biological assay with an IL-1-dependent cell line, Northern blot analysis, and in situ hybridization. Inhibition experiments on the IL-1 activity with anti IL-1 alpha antibody also support the presence of IL-1 alpha in the supernatant of cultured parenchymal liver cells. Based on these results, we discuss the possibility of IL-1 production by parenchymal liver cells in vivo.

Entities:  

Mesh:

Substances:

Year:  1994        PMID: 8299715     DOI: 10.1006/excr.1994.1026

Source DB:  PubMed          Journal:  Exp Cell Res        ISSN: 0014-4827            Impact factor:   3.905


  1 in total

1.  An inducible autocrine cascade regulates rat hepatocyte proliferation and apoptosis responses to tumor necrosis factor-alpha.

Authors:  Benjamin D Cosgrove; Connie Cheng; Justin R Pritchard; Donna B Stolz; Douglas A Lauffenburger; Linda G Griffith
Journal:  Hepatology       Date:  2008-07       Impact factor: 17.425

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.