Literature DB >> 8299677

Ivermectin levels in human breastmilk.

J E Ogbuokiri1, B C Ozumba, P O Okonkwo.   

Abstract

Ivermectin levels were measured in breastmilk and plasma of 4 healthy mothers after an oral 150 micrograms/kg dose. Mean +/- S.D. plasma and milk values were 37.9 +/- 0.54 and 14.13 +/- 0.43 (ng/ml) respectively. Steady-state ivermectin levels in milk were low. Our results suggest that exclusion of lactating mothers from mass chemotherapy with ivermectin may be unnecessary.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8299677     DOI： 10.1007/BF00265962

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


  12 in total

1.  Adverse events following mass ivermectin therapy for onchocerciasis.

Authors:  C P Chijioke; P O Okonkwo
Journal:  Trans R Soc Trop Med Hyg       Date:  1992 May-Jun       Impact factor: 2.184

2.  Periodic reproduction of Onchocerca volvulus.

Authors:  H Schulz-Key; M Karam
Journal:  Parasitol Today       Date:  1986-10

3.  Treatment of onchocerciasis with ivermectin in Sierra Leone.

Authors:  J Whitworth
Journal:  Parasitol Today       Date:  1992-04

4.  Tolerance of single high-dose ivermectin for treatment of lymphatic filariasis.

Authors:  D G Addiss; M L Eberhard; P J Lammie; W L Hitch; H C Spencer
Journal:  Trans R Soc Trop Med Hyg       Date:  1991 Mar-Apr       Impact factor: 2.184

5.  The relative systemic availability of ivermectin after administration as capsule, tablet, and oral solution.

Authors:  G Edwards; A Dingsdale; N Helsby; M L Orme; A M Breckenridge
Journal:  Eur J Clin Pharmacol       Date:  1988       Impact factor: 2.953

6.  Efficacy and tolerance of ivermectin in human onchocerciasis.

Authors:  M A Aziz; S Diallo; I M Diop; M Lariviere; M Porta
Journal:  Lancet       Date:  1982-07-24       Impact factor: 79.321

7.  Ivermectin binds avidly to plasma proteins.

Authors:  U Klotz; J E Ogbuokiri; P O Okonkwo
Journal:  Eur J Clin Pharmacol       Date:  1990       Impact factor: 2.953

8.  Double-blind study of ivermectin and diethylcarbamazine in African onchocerciasis patients with ocular involvement.

Authors:  M Lariviere; P Vingtain; M Aziz; B Beauvais; D Weimann; F Derouin; J Ginoux; H Schulz-Key; P Gaxotte; D Basset
Journal:  Lancet       Date:  1985-07-27       Impact factor: 79.321

9.  Protein binding and ivermectin estimations in patients with onchocerciasis.

Authors:  P O Okonkwo; J E Ogbuokiri; E Ofoegbu; U Klotz
Journal:  Clin Pharmacol Ther       Date:  1993-04       Impact factor: 6.875

10.  Environmental consequences of treating cattle with the antiparasitic drug ivermectin.

Authors:  R Wall; L Strong
Journal:  Nature       Date:  1987 Jun 4-10       Impact factor: 49.962
View more
  8 in total

Review 1.  The pharmacokinetics and interactions of ivermectin in humans--a mini-review.

Authors:  Aránzazu González Canga; Ana M Sahagún Prieto; M José Diez Liébana; Nélida Fernández Martínez; Matilde Sierra Vega; Juan J García Vieitez
Journal:  AAPS J       Date:  2008-01-25       Impact factor: 4.009

2.  Lactational exposure to abamectin induced mortality and adverse biochemical and histopathological effects in suckling pups.

Authors:  Abdel-Tawab H Mossa; Mona A Abdel Rasoul; Samia M M Mohafrash
Journal:  Environ Sci Pollut Res Int       Date:  2017-03-03       Impact factor: 4.223

Review 3.  Moxidectin and the avermectins: Consanguinity but not identity.

Authors:  Roger Prichard; Cécile Ménez; Anne Lespine
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2012-04-14       Impact factor: 4.077

4.  Assessment of community's knowledge, attitude and practice about onchocerciasis and community directed treatment with Ivermectin in Quara District, north western Ethiopia.

Authors:  Fitsum Weldegebreal; Girmay Medhin; Zemichael Weldegebriel; Mengistu Legesse
Journal:  Parasit Vectors       Date:  2014-03-10       Impact factor: 3.876

5.  Scabies-infested pregnant women: A critical therapeutic challenge.

Authors:  Amandine Weill; Charlotte Bernigaud; Mourad Mokni; Sophie Gil; Elisabeth Elefant; Olivier Chosidow
Journal:  PLoS Negl Trop Dis       Date:  2021-01-07

6.  Electrochemical Detection of Ivermectin Used for the Treatment of COVID-19 with Glutardialdehyde-Modified Glassy Carbon Electrode.

Authors:  Berna Koçak; Yeliz İpek
Journal:  Electrocatalysis (N Y)       Date:  2022-01-05       Impact factor: 2.933

7.  Ivermectin to reduce malaria transmission: a research agenda for a promising new tool for elimination.

Authors:  Carlos J Chaccour; Kevin C Kobylinski; Quique Bassat; Teun Bousema; Chris Drakeley; Pedro Alonso; Brian D Foy
Journal:  Malar J       Date:  2013-05-07       Impact factor: 2.979

Review 8.  Ivermectin to reduce malaria transmission I. Pharmacokinetic and pharmacodynamic considerations regarding efficacy and safety.

Authors:  Carlos Chaccour; Felix Hammann; N Regina Rabinovich
Journal:  Malar J       Date:  2017-04-24       Impact factor: 2.979
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.