Literature DB >> 8296801

IgE plasma cell leukemia successfully treated with combination VAD (vincristine, doxorubicin, dexamethasone) and MP (melphalan, prednisolone) followed by interferon-alpha.

N Yamagata1, C Shimazaki, H Goto, T Hirata, E Ashihara, N Oku, T Inaba, N Fujita, M Nakagawa.   

Abstract

A 69-year-old woman with IgE/kappa plasma cell leukemia (PCL) was treated with a sequential combination of VAD (vincristine, doxorubicin, dexamethasone) and MP (melphalan, prednisolone) followed by interferon-alpha (IFN alpha). A complete remission was achieved for 14 months. Maintenance therapy with IFN alpha has continued for an additional 10 months. IgE PCL is extremely rare. The biological characteristics of the myeloma cells, including surface marker, adhesion molecule, karyotype, DNA analysis, and the response to various cytokines, are presented.

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Year:  1994        PMID： 8296801     DOI： 10.1002/ajh.2830450315

Source DB:  PubMed          Journal:  Am J Hematol        ISSN： 0361-8609            Impact factor:   10.047


  6 in total

1.  Nonsecretory primary plasma cell leukemia with good response to thalidomide-based treatment.

Authors:  P Brück; S Mousset; A Bühme; D Hoelzer; J Atta
Journal:  Int J Hematol       Date:  2007-07       Impact factor: 2.490

Review 2.  Plasma cell leukaemia and other aggressive plasma cell malignancies.

Authors:  Taimur Sher; Kena C Miller; George Deeb; Kelvin Lee; Asher Chanan-Khan
Journal:  Br J Haematol       Date:  2010-08       Impact factor: 6.998

3.  An unusual case of IgE-multiple myeloma presenting with systemic amyloidosis 2 years after cervical plasmacytoma resection.

Authors:  Masao Hagihara; Jian Hua; Morihiro Inoue; Naohiko Michikawa
Journal:  Int J Hematol       Date:  2010-08-10       Impact factor: 2.490

4.  Primary plasma cell leukemia with extensive dense osteosclerosis: complete remission following combination chemotherapy.

Authors:  M C Kuo; L Y Shih
Journal:  Ann Hematol       Date:  1995-09       Impact factor: 3.673

5.  Prozone effect of serum IgE levels in a case of plasma cell leukemia.

Authors:  Giampaolo Talamo; William Castellani; Nathan G Dolloff
Journal:  J Hematol Oncol       Date:  2010-09-10       Impact factor: 17.388

Review 6.  Plasma cell leukemia producing monoclonal immunoglobulin E.

Authors:  Yuzuru Takemura; Masanobu Ikeda; Kahori Kobayashi; Yuji Nakazawa; Yuichi Mori; Toshimi Mitsuishi; Hiroki Ishigame; Fumiko Kameko; Kiyotaka Fujita; Ryo Ichinohasama
Journal:  Int J Hematol       Date:  2009-08-29       Impact factor: 2.490
  6 in total

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