Literature DB >> 8290586

Function of a human cyclin gene as an oncogene.

P W Hinds1, S F Dowdy, E N Eaton, A Arnold, R A Weinberg.   

Abstract

The cyclin D1 (PRAD1, CCND1) gene is affected by translocations and amplification in the genomes of a number of human tumors, suggesting that these changes confer growth advantage on developing tumor cell clones. We show here that in cultured cells, a cDNA clone of the cyclin D1 gene can contribute to cell transformation by complementing a defective adenovirus E1A oncogene. In such cells, this candidate oncogene indeed functions like an oncogene, suggesting a similar role in tumor progression in vivo.

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Year:  1994        PMID： 8290586      PMCID： PMC43018          DOI： 10.1073/pnas.91.2.709

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  48 in total

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Authors:  S P Chellappan; S Hiebert; M Mudryj; J M Horowitz; J R Nevins
Journal:  Cell       Date:  1991-06-14       Impact factor: 41.582

Review 2.  Mitotic control.

Authors:  J L Maller
Journal:  Curr Opin Cell Biol       Date:  1991-04       Impact factor: 8.382

3.  PRAD1, a candidate BCL1 oncogene: mapping and expression in centrocytic lymphoma.

Authors:  C L Rosenberg; E Wong; E M Petty; A E Bale; Y Tsujimoto; N L Harris; A Arnold
Journal:  Proc Natl Acad Sci U S A       Date:  1991-11-01       Impact factor: 11.205

4.  Rearrangement and overexpression of D11S287E, a candidate oncogene on chromosome 11q13 in benign parathyroid tumors.

Authors:  C L Rosenberg; H G Kim; T B Shows; H M Kronenberg; A Arnold
Journal:  Oncogene       Date:  1991-03       Impact factor: 9.867

5.  Human D-type cyclin.

Authors:  Y Xiong; T Connolly; B Futcher; D Beach
Journal:  Cell       Date:  1991-05-17       Impact factor: 41.582

6.  A novel cyclin encoded by a bcl1-linked candidate oncogene.

Authors:  T Motokura; T Bloom; H G Kim; H Jüppner; J V Ruderman; H M Kronenberg; A Arnold
Journal:  Nature       Date:  1991-04-11       Impact factor: 49.962

7.  Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle.

Authors:  H Matsushime; M F Roussel; R A Ashmun; C J Sherr
Journal:  Cell       Date:  1991-05-17       Impact factor: 41.582

8.  Characterization of a candidate bcl-1 gene.

Authors:  D A Withers; R C Harvey; J B Faust; O Melnyk; K Carey; T C Meeker
Journal:  Mol Cell Biol       Date:  1991-10       Impact factor: 4.272

9.  Cyclin A is required for the onset of DNA replication in mammalian fibroblasts.

Authors:  F Girard; U Strausfeld; A Fernandez; N J Lamb
Journal:  Cell       Date:  1991-12-20       Impact factor: 41.582

10.  Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast.

Authors:  D J Lew; V Dulić; S I Reed
Journal:  Cell       Date:  1991-09-20       Impact factor: 41.582
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  111 in total

Review 1.  Cell cycle regulators: mechanisms and their role in aetiology, prognosis, and treatment of cancer.

Authors:  R J Michalides
Journal:  J Clin Pathol       Date:  1999-08       Impact factor: 3.411

2.  Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4.

Authors:  E Neuman; M H Ladha; N Lin; T M Upton; S J Miller; J DiRenzo; R G Pestell; P W Hinds; S F Dowdy; M Brown; M E Ewen
Journal:  Mol Cell Biol       Date:  1997-09       Impact factor: 4.272

3.  Differentiation of human malignant melanoma cells that escape apoptosis after treatment with 9-nitrocamptothecin in vitro.

Authors:  P Pantazis; D Chatterjee; Z Han; J Wyche
Journal:  Neoplasia       Date:  1999-08       Impact factor: 5.715

4.  Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation.

Authors:  Jean-Bernard Lazaro; Peter J Bailey; Andrew B Lassar
Journal:  Genes Dev       Date:  2002-07-15       Impact factor: 11.361

5.  Lessons from a decade of integrating cancer copy number alterations with gene expression profiles.

Authors:  Norman Huang; Parantu K Shah; Cheng Li
Journal:  Brief Bioinform       Date:  2011-09-23       Impact factor: 11.622

6.  CCND1 G870A polymorphism and risk for head and neck cancer: a meta-analysis.

Authors:  Chunbo Tang; Zhanwei Wang; Jinhua Yu; Yunong Wu; Zhijun Zhu; Ning Chen
Journal:  Med Oncol       Date:  2010-05-05       Impact factor: 3.064

Review 7.  CDK6-a review of the past and a glimpse into the future: from cell-cycle control to transcriptional regulation.

Authors:  A-S Tigan; F Bellutti; K Kollmann; G Tebb; V Sexl
Journal:  Oncogene       Date:  2015-10-26       Impact factor: 9.867

8.  Genome-wide screening of indicator genes for assessing the potential carcinogenic risk of Nanjing city drinking water.

Authors:  Rui Zhang; Shupei Cheng; Aimin Li; Jie Sun; Yan Zhang; Xuxiang Zhang
Journal:  Ecotoxicology       Date:  2011-03-22       Impact factor: 2.823

9.  Requirement of cyclin E-Cdk2 inhibition in p16(INK4a)-mediated growth suppression.

Authors:  H Jiang; H S Chou; L Zhu
Journal:  Mol Cell Biol       Date:  1998-09       Impact factor: 4.272

10.  Cell cycle regulation of the cyclin A gene promoter is mediated by a variant E2F site.

Authors:  A Schulze; K Zerfass; D Spitkovsky; S Middendorp; J Bergès; K Helin; P Jansen-Dürr; B Henglein
Journal:  Proc Natl Acad Sci U S A       Date:  1995-11-21       Impact factor: 11.205
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