| Literature DB >> 8288943 |
Abstract
Mononuclear phagocytes are an important in vivo source of a wide range of complement components. They are able to rapidly up-regulate or down-regulate complement synthesis in response to many different pharmacological and biological stimuli. This ability is likely to make a significant contribution to maintaining host defences particularly in peripheral tissues. The important role of molecular biology in the study of complement biosynthesis by mononuclear phagocytes will be emphasised.Mesh:
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Year: 1993 PMID: 8288943 DOI: 10.1007/BF02918254
Source DB: PubMed Journal: Immunol Res ISSN: 0257-277X Impact factor: 2.829