Literature DB >> 8287685

Assignment of the human gene encoding the epidermal serine proteinase inhibitor SKALP (PI3) to chromosome region 20q12-->q13.

H O Molhuizen1, P L Zeeuwen, D Olde Weghuis, A Geurts van Kessel, J Schalkwijk.   

Abstract

Recently we isolated a cDNA clone corresponding to an epidermal serine proteinase inhibitor named SKALP (skin-derived antileukoproteinase). Here we report the chromosomal localization of the human gene encoding SKALP by Southern blot analysis of a panel of human x hamster hybrid cell lines and by nonradioactive in situ hybridization on R-banded human lymphocyte chromosome spreads. The SKALP-encoding gene has been assigned the approved symbol PI3 by the Human Gene Mapping nomenclature committee.

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Year:  1994        PMID: 8287685     DOI: 10.1159/000133683

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN: 0301-0171


  6 in total

1.  A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein.

Authors:  Adam Clauss; Hans Lilja; Ake Lundwall
Journal:  Biochem J       Date:  2002-11-15       Impact factor: 3.857

2.  Skin-derived antileukoproteinase (SKALP) is decreased in pustular forms of psoriasis. A clue to the pathogenesis of pustule formation?

Authors:  A L Kuijpers; P L Zeeuwen; G J de Jongh; P C van de Kerkhof; H A Alkemade; J Schalkwijk
Journal:  Arch Dermatol Res       Date:  1996-10       Impact factor: 3.017

Review 3.  The trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide core.

Authors:  J Schalkwijk; O Wiedow; S Hirose
Journal:  Biochem J       Date:  1999-06-15       Impact factor: 3.857

4.  Constitutive and inducible expression of SKALP/elafin provides anti-elastase defense in human epithelia.

Authors:  R Pfundt; F van Ruissen; I M van Vlijmen-Willems; H A Alkemade; P L Zeeuwen; P H Jap; H Dijkman; J Fransen; H Croes; P E van Erp; J Schalkwijk
Journal:  J Clin Invest       Date:  1996-09-15       Impact factor: 14.808

5.  Expression of SKALP/elafin during wound healing in human skin.

Authors:  B H van Bergen; M P Andriessen; K I Spruijt; P C van de Kerkhof; J Schalkwijk
Journal:  Arch Dermatol Res       Date:  1996-07       Impact factor: 3.017

Review 6.  The role of genomics and genetics in pulmonary arterial hypertension.

Authors:  Emilia M Swietlik; Stefan Gräf; Nicholas W Morrell
Journal:  Glob Cardiol Sci Pract       Date:  2020-04-30
  6 in total

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