Literature DB >> 8286929

Investigations of oligodeoxyinosine for triple helix formation.

J S Hogeland1, D D Weller.   

Abstract

The ability of a 17-mer of deoxyinosine to form a triple helix with a (dT)17(dA)17 segment of a 29-mer Watson-Crick duplex was investigated. Under conditions amenable to triple helix formation, (dT)17 showed evidence of complex formation as evidenced by UV melting curves and gel mobility shift assays whereas (dI)17 did not.

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Year:  1993        PMID: 8286929     DOI: 10.1089/ard.1993.3.285

Source DB:  PubMed          Journal:  Antisense Res Dev        ISSN: 1050-5261


  2 in total

1.  The effect of amino groups on the stability of DNA duplexes and triplexes based on purines derived from inosine.

Authors:  E Cubero; R Güimil-García; F J Luque; R Eritja; M Orozco
Journal:  Nucleic Acids Res       Date:  2001-06-15       Impact factor: 16.971

2.  Triplexator: detecting nucleic acid triple helices in genomic and transcriptomic data.

Authors:  Fabian A Buske; Denis C Bauer; John S Mattick; Timothy L Bailey
Journal:  Genome Res       Date:  2012-05-01       Impact factor: 9.043

  2 in total

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