Literature DB >> 8282830

Post mortem examinations of HIV infected patients: a nationwide survey.

J Davies1, I P Everall, P L Lantos.   

Abstract

AIMS: To identify the number and geographical distribution of post mortem examinations performed on HIV infected cadavers; to identify the areas that perform post mortem examinations so that, by invitation and discussion, a national post mortem network could be initiated.
METHODS: A nationwide survey of Royal College of Pathologists' district tutors (n = 216) was done by postal questionnaire. These were completed by the district tutors or passed on to their histopathologist colleagues. The results were collated after three months. After one follow up letter, an 86% response rate, which is a significant sample, was achieved.
RESULTS: Twenty eight per cent of respondents were performing HIV post mortem examinations. Of those who were not performing them (30%), the lack of clinical or coroner requests was the most common explanation. All regions provide facilities for HIV post mortem examinations, as judged by the responses.
CONCLUSIONS: These findings are of singular importance as it is the first United Kingdom survey investigating the distribution of post mortem examinations on HIV infected cadavers. Studying post mortem material using a systemic, coordinated collection of brain tissue is essential to increase knowledge of a new disease of pandemic proportions.

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Mesh:

Year:  1993        PMID: 8282830      PMCID: PMC501713          DOI: 10.1136/jcp.46.12.1076

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  21 in total

Review 1.  HIV-associated disease of the nervous system: review of nomenclature and proposal for neuropathology-based terminology.

Authors:  H Budka; C A Wiley; P Kleihues; J Artigas; A K Asbury; E S Cho; D R Cornblath; M C Dal Canto; U DeGirolami; D Dickson
Journal:  Brain Pathol       Date:  1991-04       Impact factor: 6.508

2.  Multinucleated giant cells and HTLV-III in AIDS encephalopathy.

Authors:  L R Sharer; E S Cho; L G Epstein
Journal:  Hum Pathol       Date:  1985-08       Impact factor: 3.466

3.  The AIDS dementia complex: I. Clinical features.

Authors:  B A Navia; B D Jordan; R W Price
Journal:  Ann Neurol       Date:  1986-06       Impact factor: 10.422

4.  Neuronal loss in the frontal cortex in HIV infection.

Authors:  I P Everall; P J Luthert; P L Lantos
Journal:  Lancet       Date:  1991-05-11       Impact factor: 79.321

5.  The future of the autopsy.

Authors:  F Goodale
Journal:  Am J Clin Pathol       Date:  1978-02       Impact factor: 2.493

6.  Neuropathology of acquired immunodeficiency syndrome (AIDS): an autopsy review.

Authors:  C K Petito; E S Cho; W Lemann; B A Navia; R W Price
Journal:  J Neuropathol Exp Neurol       Date:  1986-11       Impact factor: 3.685

Review 7.  Psychiatric manifestations of HIV disease.

Authors:  J Catalan
Journal:  Baillieres Clin Gastroenterol       Date:  1990-06

Review 8.  The brain in AIDS: central nervous system HIV-1 infection and AIDS dementia complex.

Authors:  R W Price; B Brew; J Sidtis; M Rosenblum; A C Scheck; P Cleary
Journal:  Science       Date:  1988-02-05       Impact factor: 47.728

9.  Value of necropsy in acquired immunodeficiency syndrome.

Authors:  M S Wilkes; A H Fortin; J C Felix; T A Godwin; W G Thompson
Journal:  Lancet       Date:  1988-07-09       Impact factor: 79.321

10.  Isolation of HTLV-III from cerebrospinal fluid and neural tissues of patients with neurologic syndromes related to the acquired immunodeficiency syndrome.

Authors:  D D Ho; T R Rota; R T Schooley; J C Kaplan; J D Allan; J E Groopman; L Resnick; D Felsenstein; C A Andrews; M S Hirsch
Journal:  N Engl J Med       Date:  1985-12-12       Impact factor: 91.245

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  2 in total

1.  HIV and the necropsy.

Authors:  S B Lucas
Journal:  J Clin Pathol       Date:  1993-12       Impact factor: 3.411

2.  Comparison of magnetic resonance imaging with neuropathological findings in the diagnosis of HIV and CMV associated CNS disease in AIDS.

Authors:  R F Miller; S B Lucas; M A Hall-Craggs; N S Brink; F Scaravilli; R J Chinn; B E Kendall; I G Williams; M J Harrison
Journal:  J Neurol Neurosurg Psychiatry       Date:  1997-04       Impact factor: 10.154

  2 in total

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