Literature DB >> 8282262

Toxic megacolon: the knee-elbow position relieves bowel distension.

M Z Panos1, M J Wood, P Asquith.   

Abstract

Toxic megacolon complicating inflammatory or infective colitis carries a high morbidity and mortality and surgical intervention is necessary in up to 80% of cases. Perforation complicates toxic megacolon in about 35% of cases. After perforation, the death rate nears 50%. Gaseous distension of the bowel causes considerable discomfort to the patient and increases transmural pressure. The latter is thought to cause a reduction in blood flow and may predispose to perforation. The use of instruments for colonic aspiration is discouraged, because of the high risk of perforation. The successful use of the knee-elbow position to relieve bowel distension in two patients with toxic megacolon is described.

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Year:  1993        PMID: 8282262      PMCID: PMC1374472          DOI: 10.1136/gut.34.12.1726

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


  7 in total

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Journal:  Gastroenterology       Date:  1969-07       Impact factor: 22.682

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Journal:  Medicine (Baltimore)       Date:  1969-05       Impact factor: 1.889

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Authors:  C S Grant; R R Dozois
Journal:  Am J Surg       Date:  1984-01       Impact factor: 2.565

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Authors:  A J Greenstein; D B Sachar; A Gibas; D Schrag; T Heimann; H D Janowitz; A H Aufses
Journal:  J Clin Gastroenterol       Date:  1985-04       Impact factor: 3.062

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Authors:  T J Muscroft; P M Warren; P Asquith; R D Montgomery; G S Sokhi
Journal:  Postgrad Med J       Date:  1981-04       Impact factor: 2.401

7.  Toxic megacolon. Significant improvement in surgical management.

Authors:  N A Odyniec; E S Judd; W G Sauer
Journal:  Arch Surg       Date:  1967-05
  7 in total
  10 in total

Review 1.  [Toxic megacolon].

Authors:  M Leppkes; M Ganslmayer; R Strauß; M F Neurath
Journal:  Med Klin Intensivmed Notfmed       Date:  2015-09-14       Impact factor: 0.840

2.  Leukocytapheresis (LCAP) for management of fulminant ulcerative colitis with toxic megacolon.

Authors:  Koji Sawada; Akimitsu Egashira; Kunio Ohnishi; Ken Fukunaga; Takeshi Kusaka; Takashi Shimoyama
Journal:  Dig Dis Sci       Date:  2005-04       Impact factor: 3.199

3.  Letters to the editor.

Authors:  R R Babb
Journal:  Gut       Date:  1994-08       Impact factor: 23.059

4.  Acute Colonic Pseudo-Obstruction (Ogilvie's Syndrome).

Authors:  Jan Tack
Journal:  Curr Treat Options Gastroenterol       Date:  2006-07

5.  Toxic megacolon associated Clostridium difficile colitis.

Authors:  Leena Sayedy; Darshan Kothari; Robert J Richards
Journal:  World J Gastrointest Endosc       Date:  2010-08-16

Review 6.  Management of inflammatory bowel disease.

Authors:  M Nayar; J M Rhodes
Journal:  Postgrad Med J       Date:  2004-04       Impact factor: 2.401

Review 7.  Strategies for the care of adults hospitalized for active ulcerative colitis.

Authors:  Suresh Pola; Derek Patel; Sonia Ramamoorthy; Elisabeth McLemore; Marianne Fahmy; Jesus Rivera-Nieves; John T Chang; Elisabeth Evans; Michael Docherty; Mark Talamini; William J Sandborn
Journal:  Clin Gastroenterol Hepatol       Date:  2012-07-24       Impact factor: 11.382

8.  HSV1/2 Genital Infection in Mice Cause Reversible Delayed Gastrointestinal Transit: A Model for Enteric Myopathy.

Authors:  Arun Chaudhury; Vijaya Sena Reddy Dendi; Mousumi Chaudhury; Astha Jain; Madhukar Reddy Kasarla; Kiran Panuganti; Gaurav Jain; Abhijit Ramanujam; Bhavin Rena; Sudheer Reddy Koyagura; Sumit Fogla; Sunil Kumar; Nawal Singh Shekhawat; Srinivas Maddur
Journal:  Front Med (Lausanne)       Date:  2018-07-17

9.  Toxic Megacolon and Acute Ischemia of the Colon due to Sigmoid Stenosis Related to Diverticulitis.

Authors:  P Antonopoulos; M Almyroudi; V Kolonia; S Kouris; N Troumpoukis; N Economou
Journal:  Case Rep Gastroenterol       Date:  2013-09-11

Review 10.  Toxic Megacolon: Background, Pathophysiology, Management Challenges and Solutions.

Authors:  Jiten Desai; Mohamed Elnaggar; Ahmed A Hanfy; Rajkumar Doshi
Journal:  Clin Exp Gastroenterol       Date:  2020-05-19
  10 in total

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