Literature DB >> 8281754

Hemorrhagic and Mojave toxins in the venoms of the offspring of two Mojave rattlesnakes (Crotalus scutulatus scutulatus).

E D Rael1, C S Lieb, N Maddux, A Varela-Ramirez, J Perez.   

Abstract

1. The venoms of two Mojave rattlesnakes and those of their offsprings were analyzed for Mojave toxin and hemorrhagic toxin. 2. The venom of one female, collected in Pima County, Arizona, and the venoms of her six offspring contained hemorrhagic toxin but not Mojave toxin (venom B). 3. The venom of the second female, captured in El Paso County, Texas, contained both toxins (A+B venom). Of her 10 offspring, five contained venom with both toxins, two had hemorrhagic toxin only, and three contained neither toxin. 4. Venoms that caused hemorrhage also inactivated complement. A pool of the venoms of the venom B offspring was less toxic than adult pooled venom A.

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Year:  1993        PMID： 8281754     DOI： 10.1016/0305-0491(93)90136-s

Source DB:  PubMed          Journal:  Comp Biochem Physiol B        ISSN： 0305-0491


  6 in total

1.  Molecular models of the Mojave rattlesnake (Crotalus scutulatus scutulatus) venom metalloproteinases reveal a structural basis for differences in hemorrhagic activities.

Authors:  Ruben K Dagda; Sardar E Gasanov; Boris Zhang; William Welch; Eppie D Rael
Journal:  J Biol Phys       Date:  2014-02-13       Impact factor: 1.365

2.  Rattling the border wall: Pathophysiological implications of functional and proteomic venom variation between Mexican and US subspecies of the desert rattlesnake Crotalus scutulatus.

Authors:  James Dobson; Daryl C Yang; Bianca Op den Brouw; Chip Cochran; Tam Huynh; Sanjaya Kurrupu; Elda E Sánchez; Daniel J Massey; Kate Baumann; Timothy N W Jackson; Amanda Nouwens; Peter Josh; Edgar Neri-Castro; Alejandro Alagón; Wayne C Hodgson; Bryan G Fry
Journal:  Comp Biochem Physiol C Toxicol Pharmacol       Date:  2017-10-24       Impact factor: 3.228

3.  Molecular evolution and structure-function relationships of crotoxin-like and asparagine-6-containing phospholipases A2 in pit viper venoms.

Authors:  Yi-Hsuan Chen; Ying-Ming Wang; Ming-Jhy Hseu; Inn-Ho Tsai
Journal:  Biochem J       Date:  2004-07-01       Impact factor: 3.857

4.  Cytotoxic effects of Pseudocerastes persicus venom and its HPLC fractions on lung cancer cells.

Authors:  Benyamin Shahbazi; Zahra Salehi Najafabadi; Hamidreza Goudarzi; Mahnaz Sajadi; Fatemeh Tahoori; Masoumeh Bagheri
Journal:  J Venom Anim Toxins Incl Trop Dis       Date:  2019-09-16

5.  Genetic Basis for Variation of Metalloproteinase-Associated Biochemical Activity in Venom of the Mojave Rattlesnake (Crotalus scutulatus scutulatus).

Authors:  Ruben K Dagda; Sardar Gasanov; Ysidro De La Oiii; Eppie D Rael; Carl S Lieb
Journal:  Biochem Res Int       Date:  2013-07-29

6.  Snake Venom Cytotoxins, Phospholipase A2s, and Zn2+-dependent Metalloproteinases: Mechanisms of Action and Pharmacological Relevance.

Authors:  Sardar E Gasanov; Ruben K Dagda; Eppie D Rael
Journal:  J Clin Toxicol       Date:  2014-01-25
  6 in total

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