| Literature DB >> 8279812 |
N Mahmood1, C Pizza, R Aquino, N De Tommasi, S Piacente, S Colman, A Burke, A J Hay.
Abstract
Of a variety of flavanoids, the flavans were generally more effective than flavones and flavanones in selective inhibition of HIV-1, HIV-2 or SIV infection. Studies of their effects on the binding of sCD4 and antibody to gp120 indicated that the effective compounds interact irreversibly with gp120 to inactive virus infectivity and block infection.Entities:
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Year: 1993 PMID: 8279812 DOI: 10.1016/0166-3542(93)90095-z
Source DB: PubMed Journal: Antiviral Res ISSN: 0166-3542 Impact factor: 5.970