Literature DB >> 82784

Effect of myo-inositol on peripheral-nerve function in diabetes.

J G Salway, L Whitehead, J A Finnegan, A Karunanayaka, D Barnett, R B Payne.   

Abstract

myo-Inositol, 500 mg twice a day, given to seven diabetic patients for two weeks, increased the amplitude of the evoked action potentials of the median, sural, and popliteal nerves by an average of 76%, 160%, and 40%, respectively. There was no significant change in the conduction velocities of these nerves, myo-Inositol may be valuable in the treatment of diabetic neuropathy.

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Year:  1978        PMID: 82784     DOI: 10.1016/s0140-6736(78)92043-3

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  17 in total

Review 1.  Aldose reductase inhibitors in the treatment of diabetic neuropathy. A review of the rationale and clinical evidence.

Authors:  E A Masson; A J Boulton
Journal:  Drugs       Date:  1990-02       Impact factor: 9.546

2.  Nutritional composition and antioxidant activity of Spanish and Virginia groundnuts (Arachis hypogaea L.): a comparative study.

Authors:  M K Mahatma; L K Thawait; S K Bishi; N Khatediya; A L Rathnakumar; H B Lalwani; J B Misra
Journal:  J Food Sci Technol       Date:  2016-06-18       Impact factor: 2.701

Review 3.  The biochemistry of diabetes.

Authors:  R Taylor; L Agius
Journal:  Biochem J       Date:  1988-03-15       Impact factor: 3.857

Review 4.  Sorbitol, myo-inositol and sodium-potassium ATPase in diabetic peripheral nerve.

Authors:  D A Greene
Journal:  Drugs       Date:  1986       Impact factor: 9.546

5.  Treatment of peripheral neuropathies.

Authors:  M Hallett; D Tandon; A Berardelli
Journal:  J Neurol Neurosurg Psychiatry       Date:  1985-12       Impact factor: 10.154

6.  A defect in sodium-dependent amino acid uptake in diabetic rabbit peripheral nerve. Correction by an aldose reductase inhibitor or myo-inositol administration.

Authors:  D A Greene; S A Lattimer; P B Carroll; J D Fernstrom; D N Finegold
Journal:  J Clin Invest       Date:  1990-05       Impact factor: 14.808

7.  Myo-inositol and sorbitol metabolism in relation to peripheral nerve function in experimental diabetes in the rat: the effect of aldose reductase inhibition.

Authors:  K R Gillon; J N Hawthorne; D R Tomlinson
Journal:  Diabetologia       Date:  1983-10       Impact factor: 10.122

8.  Influence of glucoregulation with continuous subcutaneous insulin infusion on nerve conduction velocity and beat to beat variation in diabetics.

Authors:  S Gambardella; A Napoli; V Spallone; A M Verrastro; R Lazzari; C Geraldini; G Sideri; G Menzinger
Journal:  J Endocrinol Invest       Date:  1983-10       Impact factor: 4.256

Review 9.  Diabetic autonomic neuropathy.

Authors:  B F Clarke; D J Ewing; I W Campbell
Journal:  Diabetologia       Date:  1979-10       Impact factor: 10.122

10.  Sodium- and energy-dependent uptake of myo-inositol by rabbit peripheral nerve. Competitive inhibition by glucose and lack of an insulin effect.

Authors:  D A Greene; S A Lattimer
Journal:  J Clin Invest       Date:  1982-11       Impact factor: 14.808

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