Literature DB >> 827755

Climbing behavior induced by apomorphine in mice: a simple test for the study of dopamine receptors in striatum.

P Protais, J Costentin, J C Schwartz.   

Abstract

Mice treated with low doses of apomorphine tend to adopt a vertical position along the walls of their cage. Optimal conditions have been defined to obtain a reliable dose-response relationship. This peculiar behavior appears to be elicited by stimulation of dopamine receptors in the striatum: it is suppressed after coagulation of this structure while it is facilitated when these receptors are made hypersensitive by previous treatments with 6-hydroxy-dopamine or haloperidol; on the other hand, it is not modified by coagulation of the nucleus accumbens. The relative efficacy of various agonists and antagonists of dopamine receptors have been determined on this test. It appears that this stereotyped behavior might represent a convenient mean to assess the stimulation of striatal dopamine receptors in mice.

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Year:  1976        PMID： 827755     DOI： 10.1007/BF00634146

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  19 in total

1.  Narcotic withdrawal like mouse jumping produced by amphetamine and L-DOPA.

Authors:  H Lal; F C Colpaert; P Laduron
Journal:  Eur J Pharmacol       Date:  1975-01       Impact factor: 4.432

2.  Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse.

Authors:  T J HALEY; W G MCCORMICK
Journal:  Br J Pharmacol Chemother       Date:  1957-03

3.  Increased sensitivity to dopaminergic agents after chronic neuroleptic treatment.

Authors:  P F Vonvoigtlander; E G Losey; H J Triezenberg
Journal:  J Pharmacol Exp Ther       Date:  1975-04       Impact factor: 4.030

4.  Postsynaptic supersensitivity after 6-hydroxy-dopamine induced degeneration of the nigro-striatal dopamine system.

Authors:  U Ungerstedt
Journal:  Acta Physiol Scand Suppl       Date:  1971

5.  Evidence for dopamine receptor stimulation by apomorphine.

Authors:  N E Andén; A Rubenson; K Fuxe; T Hökfelt
Journal:  J Pharm Pharmacol       Date:  1967-09       Impact factor: 3.765

6.  Behavioral evidence for dopaminergic supersensitivity after chronic haloperidol.

Authors:  G Gianutsos; R B Drawbaugh; M D Hynes; H Lal
Journal:  Life Sci       Date:  1974-03-01       Impact factor: 5.037

7.  A comparison of effects of apomorphine and ET495 on locomotor activity and circling behaviour in mice.

Authors:  J E Thornburg; K E Moore
Journal:  Neuropharmacology       Date:  1974-03       Impact factor: 5.250

8.  Altered response to apomorphine in 6-hydroxydopamine-treated rats.

Authors:  R Schoenfeld; N Uretsky
Journal:  Eur J Pharmacol       Date:  1972-07       Impact factor: 4.432

9.  [Intraspecific aggressive behavior induced by apomorphine in the rat].

Authors:  B Senault
Journal:  Psychopharmacologia       Date:  1970

10.  Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum.

Authors:  P H Kelly; P W Seviour; S D Iversen
Journal:  Brain Res       Date:  1975-09-05       Impact factor: 3.252
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  63 in total

1.  Mode of action of apomorphine and dexamphetamine on gnawing compulsion in rats: A.M. Ernst. Psychopharmacologia (Berl.) 10, 316-323 (1967)

Authors:  T W Robbins; D de Wied
Journal:  Psychopharmacology (Berl)       Date:  1991       Impact factor: 4.530

2.  Behavioural effects of the methanolic root bark extract of Securinega virosa in rodents.

Authors:  M G Magaji; J A Anuka; I Abdu-Aguye; A H Yaro; I M Hussaini
Journal:  Afr J Tradit Complement Altern Med       Date:  2008-01-22

3.  Differential actions of typical and atypical neuroleptic agents on two behavioural effects of apomorphine in the mouse [proceedings].

Authors:  B Costall; R J Naylor; V Nohria
Journal:  Br J Pharmacol       Date:  1978-06       Impact factor: 8.739

4.  YKP1447, A Novel Potential Atypical Antipsychotic Agent.

Authors:  Seon Min Dong; Yong Gil Kim; Joon Heo; Mi Kyung Ji; Jeong Woo Cho; Byong Sung Kwak
Journal:  Korean J Physiol Pharmacol       Date:  2009-04-30       Impact factor: 2.016

5.  Seroquel: behavioral effects in conventional and novel tests for atypical antipsychotic drug.

Authors:  B M Migler; E J Warawa; J B Malick
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

6.  Rat climbing behavior elicited by stimulation of cerebral dopamine receptors.

Authors:  P Protais; J J Bonnet; J Costentin; J C Schwartz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1984-02       Impact factor: 3.000

7.  Unexpected potentiation by discriminant benzamide derivatives of stereotyped behaviours elicited by dopamine agonists in mice.

Authors:  M Vasse; P Protais; J Costentin; J C Schwartz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1985-04       Impact factor: 3.000

8.  Effects of discriminant and non-discriminant dopamine antagonists on in vivo accumulation of 3H-N-propyl-norapomorphine in mouse striatum and tuberculum olfactorium.

Authors:  C Gulat-Marnay; A Lafitte; J C Schwartz; P Protais
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1985-04       Impact factor: 3.000

9.  Roxindole, a potential antidepressant. I. Effect on the dopamine system.

Authors:  J Maj; K Kolodziejczyk; Z Rogóz; G Skuza
Journal:  J Neural Transm (Vienna)       Date:  1996       Impact factor: 3.575

10.  Behavioral responses to apomorphine and amphetamine in differentially housed mice.

Authors:  C A Wilmot; C Vander Wende; M T Spoerlein
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530
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