Literature DB >> 8277514

6-Azasteroids: potent dual inhibitors of human type 1 and 2 steroid 5 alpha-reductase.

S V Frye1, C D Haffner, P R Maloney, R A Mook, G F Dorsey, R N Hiner, K W Batchelor, H N Bramson, J D Stuart, S L Schweiker.   

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Year:  1993        PMID： 8277514     DOI： 10.1021/jm00078a022

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  6 in total

Review 1.  Clinical application of 5alpha-reductase inhibitors.

Authors:  A Cilotti; G Danza; M Serio
Journal:  J Endocrinol Invest       Date:  2001-03       Impact factor: 4.256

Review 2.  Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis.

Authors:  Hugues Ouellet; Jonathan B Johnston; Paul R Ortiz de Montellano
Journal:  Trends Microbiol       Date:  2011-09-15       Impact factor: 17.079

3.  Inhibition of the M. tuberculosis 3β-hydroxysteroid dehydrogenase by azasteroids.

Authors:  Suzanne T Thomas; Xinxin Yang; Nicole S Sampson
Journal:  Bioorg Med Chem Lett       Date:  2011-03-06       Impact factor: 2.823

Review 4.  Cholesterol metabolism: a potential therapeutic target in Mycobacteria.

Authors:  Areej Abuhammad
Journal:  Br J Pharmacol       Date:  2017-01-24       Impact factor: 8.739

5.  Mce3R Stress-Resistance Pathway Is Vulnerable to Small-Molecule Targeting That Improves Tuberculosis Drug Activities.

Authors:  Xinxin Yang; Tianao Yuan; Rui Ma; Kieran I Chacko; Melissa Smith; Gintaras Deikus; Robert Sebra; Andrew Kasarskis; Harm van Bakel; Scott G Franzblau; Nicole S Sampson
Journal:  ACS Infect Dis       Date:  2019-05-03       Impact factor: 5.084

6.  Reductive Power Generated by Mycobacterium leprae Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis.

Authors:  Thabatta L S A Rosa; Maria Angela M Marques; Zachary DeBoard; Kelly Hutchins; Carlos Adriano A Silva; Christine R Montague; Tianao Yuan; Julio J Amaral; Georgia C Atella; Patrícia S Rosa; Katherine A Mattos; Brian C VanderVen; Ramanuj Lahiri; Nicole S Sampson; Patrick J Brennan; John T Belisle; Maria Cristina V Pessolani; Marcia Berrêdo-Pinho
Journal:  Front Cell Infect Microbiol       Date:  2021-07-28       Impact factor: 5.293
  6 in total

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