| Literature DB >> 8277430 |
K Yamasaki1, T Otake, H Mori, M Morimoto, N Ueba, Y Kurokawa, K Shiota, T Yuge.
Abstract
The anti-HIV-1 effects of 204 crude drugs of common use in Japan were evaluated in vitro. As a result, 45 samples inhibited HIV-1-induced cytopathogenicity in MT-4 cells. In particular, the hot water extracts of Lithospermum erythrorhizon (root) and Prunella vulgaris (spike) showed the strongest anti-HIV-1 activities. Their IC100 values were both 16 micrograms/ml. In general, the hot water extracts of the crude drug suppressed the replication of HIV-1 growth more strongly than the cold water extracts.Entities:
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Year: 1993 PMID: 8277430 DOI: 10.1248/yakushi1947.113.11_818
Source DB: PubMed Journal: Yakugaku Zasshi ISSN: 0031-6903 Impact factor: 0.302