| Literature DB >> 827710 |
Abstract
The chemical induction of malignant transformation in BHK cells seems to result from a somatic mutation. Stable transformants, whose frequency is significantly increased by mutagenic carcinogens, can revert to normal and often display temperature-restricted phenotypes indicative of an altered gene product.Mesh:
Substances:
Year: 1976 PMID: 827710 DOI: 10.1038/264722a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962