Literature DB >> 827710

Somatic mutation as the basis for malignant transformation of BHK cells by chemical carcinogens.

N Bouck, G di Mayorca.   

Abstract

The chemical induction of malignant transformation in BHK cells seems to result from a somatic mutation. Stable transformants, whose frequency is significantly increased by mutagenic carcinogens, can revert to normal and often display temperature-restricted phenotypes indicative of an altered gene product.

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Year:  1976        PMID: 827710     DOI: 10.1038/264722a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  28 in total

1.  Apurinic acid endonuclease activity from mouse epidermal cells.

Authors:  G Ludwig; H W Thielmann
Journal:  Nucleic Acids Res       Date:  1979-06-25       Impact factor: 16.971

2.  Relationship between somatic mutation and neoplastic transformation.

Authors:  J C Barrett; P O Ts'o
Journal:  Proc Natl Acad Sci U S A       Date:  1978-07       Impact factor: 11.205

3.  Passage of phenotypes of chemically transformed cells via transfection of DNA and chromatin.

Authors:  C Shih; B Z Shilo; M P Goldfarb; A Dannenberg; R A Weinberg
Journal:  Proc Natl Acad Sci U S A       Date:  1979-11       Impact factor: 11.205

Review 4.  Genetics of neoplasia--impact of ecogenetics on oncogenesis. A review.

Authors:  D T Purtilo; L Paquin; T Gindhart
Journal:  Am J Pathol       Date:  1978-06       Impact factor: 4.307

5.  Temperature-sensitive growth regulation in one type of transformed rat cells induced by the tsa mutant of polyoma virus.

Authors:  R Seif; F Cuzin
Journal:  J Virol       Date:  1977-12       Impact factor: 5.103

6.  Nonstructural proteins NS2 of minute virus of mice associate in vivo with 14-3-3 protein family members.

Authors:  K Brockhaus; S Plaza; D J Pintel; J Rommelaere; N Salomé
Journal:  J Virol       Date:  1996-11       Impact factor: 5.103

7.  High-efficiency transformation of mammalian cells by plasmid DNA.

Authors:  C Chen; H Okayama
Journal:  Mol Cell Biol       Date:  1987-08       Impact factor: 4.272

8.  Mutagen-induced resistance to mycophenolic acid in hamster cells can be associated with increased inosine 5'-phosphate dehydrogenase activity.

Authors:  E Huberman; C K McKeown; J Friedman
Journal:  Proc Natl Acad Sci U S A       Date:  1981-05       Impact factor: 11.205

9.  Genetic basis of susceptibility for development of neoplasms following treatment with N-methyl-N-nitrosourea (MNU) or x-rays in the platyfish/swordtail system.

Authors:  M Schwab; J Haas; S Abdo; M R Ahuja; G Kollinger; A Anders; F Anders
Journal:  Experientia       Date:  1978-06-15

10.  Analysis of the 10q11 cancer risk locus implicates MSMB and NCOA4 in human prostate tumorigenesis.

Authors:  Mark M Pomerantz; Yashaswi Shrestha; Richard J Flavin; Meredith M Regan; Kathryn L Penney; Lorelei A Mucci; Meir J Stampfer; David J Hunter; Stephen J Chanock; Eric J Schafer; Jennifer A Chan; Josep Tabernero; José Baselga; Andrea L Richardson; Massimo Loda; William K Oh; Philip W Kantoff; William C Hahn; Matthew L Freedman
Journal:  PLoS Genet       Date:  2010-11-11       Impact factor: 5.917

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