| Literature DB >> 8276893 |
O Kuge1, S Hara-Kuge, L Orci, M Ravazzola, M Amherdt, G Tanigawa, F T Wieland, J E Rothman.
Abstract
cDNA encoding the 20-kD subunit of coatomer, zeta-COP, predicts a protein of 177-amino acid residues, similar in sequence to AP17 and AP19, subunits of the clathrin adaptor complexes. Polyclonal antibody directed to zeta-COP blocks the binding of coatomer to Golgi membranes and prevents the assembly of COP-coated vesicles on Golgi cisternae. Unlike other coatomer subunits (beta-, beta'-, gamma-, and epsilon-COP), zeta-COP exists in both coatomer bound and free pools.Entities:
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Year: 1993 PMID: 8276893 PMCID: PMC2290901 DOI: 10.1083/jcb.123.6.1727
Source DB: PubMed Journal: J Cell Biol ISSN: 0021-9525 Impact factor: 10.539