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Literature DB >> 8274858

The structure and function of yeast ARS elements.

Abstract

The past year has seen significant advances in our understanding of the structure and function of yeast ARS elements. These elements, some of which function as chromosomal origins of DNA replication, are modular in structure. An essential domain, the ARS consensus sequence, binds a multiprotein complex that might be the long-sought initiator protein. The flanking domain contains a DNA unwinding element and a binding site for a multifunctional protein that acts as a replication enhancer.

Entities: Species

Mesh：

Substances：
DNA, Fungal

Year: 1993 PMID： 8274858 DOI： 10.1016/s0959-437x(05)80094-2

Source DB: PubMed Journal: Curr Opin Genet Dev ISSN： 0959-437X Impact factor: 5.578

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Cited

95 in total

1. RNA polymerase II and III transcription factors can stimulate DNA replication by modifying origin chromatin structures.

Authors: M Bodmer-Glavas; K Edler; A Barberis
Journal: Nucleic Acids Res Date: 2001-11-15 Impact factor: 16.971

2. Strong minor groove base conservation in sequence logos implies DNA distortion or base flipping during replication and transcription initiation.

Authors: T D Schneider
Journal: Nucleic Acids Res Date: 2001-12-01 Impact factor: 16.971

3. Functional equivalency and diversity of cis-acting elements among yeast replication origins.

Authors: S Lin; D Kowalski
Journal: Mol Cell Biol Date: 1997-09 Impact factor: 4.272

4. Genome-wide distribution of DNA replication origins at A+T-rich islands in Schizosaccharomyces pombe.

Authors: Mónica Segurado; Alberto de Luis; Francisco Antequera
Journal: EMBO Rep Date: 2003-10-17 Impact factor: 8.807

5. Degradation of origin recognition complex large subunit by the anaphase-promoting complex in Drosophila.

Authors: Marito Araki; Robin P Wharton; Zhanyun Tang; Hongtao Yu; Maki Asano
Journal: EMBO J Date: 2003-11-17 Impact factor: 11.598

6. Replication of the chicken beta-globin locus: early-firing origins at the 5' HS4 insulator and the rho- and betaA-globin genes show opposite epigenetic modifications.

Authors: Marie-Noëlle Prioleau; Marie-Claude Gendron; Olivier Hyrien
Journal: Mol Cell Biol Date: 2003-05 Impact factor: 4.272

The structure and function of yeast ARS elements.

1. RNA polymerase II and III transcription factors can stimulate DNA replication by modifying origin chromatin structures.

2. Strong minor groove base conservation in sequence logos implies DNA distortion or base flipping during replication and transcription initiation.

3. Functional equivalency and diversity of cis-acting elements among yeast replication origins.

4. Genome-wide distribution of DNA replication origins at A+T-rich islands in Schizosaccharomyces pombe.

5. Degradation of origin recognition complex large subunit by the anaphase-promoting complex in Drosophila.

6. Replication of the chicken beta-globin locus: early-firing origins at the 5' HS4 insulator and the rho- and betaA-globin genes show opposite epigenetic modifications.

7. Developmental changes in the Sciara II/9A initiation zone for DNA replication.

8. The NAD(+)-dependent Sir2p histone deacetylase is a negative regulator of chromosomal DNA replication.

9. Physical mapping of origins of replication in the fission yeast Schizosaccharomyces pombe.

10. Replication initiation sites are distributed widely in the amplified CHO dihydrofolate reductase domain.