Literature DB >> 8274577

Methylphenidate increases thought disorder in recent onset schizophrenics, but not in normal controls.

D L Levy1, M Smith, D Robinson, D Jody, G Lerner, J Alvir, S H Geisler, S R Szymanski, A Gonzalez, D I Mayerhoff.   

Abstract

The effects of apomorphine and methylphenidate on thought disorder, as measured by the Thought Disorder Index, in schizophrenic patients and in normal controls were evaluated. Methylphenidate, but not apomorphine, increased thought disorder in patients. Neither drug significantly increased thought disorder in controls.

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Year:  1993        PMID: 8274577     DOI: 10.1016/0006-3223(93)90192-g

Source DB:  PubMed          Journal:  Biol Psychiatry        ISSN: 0006-3223            Impact factor:   13.382


  8 in total

Review 1.  Animal models of schizophrenia: a critical review.

Authors:  E R Marcotte; D M Pearson; L K Srivastava
Journal:  J Psychiatry Neurosci       Date:  2001-11       Impact factor: 6.186

Review 2.  Apomorphine and the dopamine hypothesis of schizophrenia: a dilemma?

Authors:  L Dépatie; S Lal
Journal:  J Psychiatry Neurosci       Date:  2001-05       Impact factor: 6.186

3.  Selective reinforcement learning deficits in schizophrenia support predictions from computational models of striatal-cortical dysfunction.

Authors:  James A Waltz; Michael J Frank; Benjamin M Robinson; James M Gold
Journal:  Biol Psychiatry       Date:  2007-02-14       Impact factor: 13.382

4.  Using computational patients to evaluate illness mechanisms in schizophrenia.

Authors:  Ralph E Hoffman; Uli Grasemann; Ralitza Gueorguieva; Donald Quinlan; Douglas Lane; Risto Miikkulainen
Journal:  Biol Psychiatry       Date:  2011-03-11       Impact factor: 13.382

Review 5.  Pharmacological manipulation of human working memory.

Authors:  Deanna M Barch
Journal:  Psychopharmacology (Berl)       Date:  2004-01-30       Impact factor: 4.530

Review 6.  Pharmacological cognitive enhancement in schizophrenia.

Authors:  Philip D Harvey
Journal:  Neuropsychol Rev       Date:  2009-06-09       Impact factor: 7.444

Review 7.  A review of the effects of modafinil on cognition in schizophrenia.

Authors:  Sharon Morein-Zamir; Danielle C Turner; Barbara J Sahakian
Journal:  Schizophr Bull       Date:  2007-07-18       Impact factor: 9.306

8.  Locomotor hyperactivity in 14-3-3ζ KO mice is associated with dopamine transporter dysfunction.

Authors:  H Ramshaw; X Xu; E J Jaehne; P McCarthy; Z Greenberg; E Saleh; B McClure; J Woodcock; S Kabbara; S Wiszniak; Ting-Yi Wang; C Parish; M van den Buuse; B T Baune; A Lopez; Q Schwarz
Journal:  Transl Psychiatry       Date:  2013-12-03       Impact factor: 6.222

  8 in total

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