| Literature DB >> 827358 |
L Orci, D Baetens, M Ravazzola, Y Stefan, F Malaisse-Lagae.
Abstract
The immunocytochemical technique for the cellular localization of hormones allows a precise identification of islet cell types responsible for the production of insulin, glucagon, somatostatin and pancreatic polypeptide. A systematic study of Rat pancreas has revealed a hitherto undescribed morphological heterogeneity of islets. In fact, the cellular composition of islets differs according to their anatomical distribution. The "PP islets" are preferentially located in the inferior 2/3 of the head of the pancreas, whilst "glucagon islets" populate the remainder of the gland.Entities:
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Year: 1976 PMID： 827358
Source DB: PubMed Journal: C R Acad Hebd Seances Acad Sci D