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Literature DB >> 827327

Prevalence of multiple antibiotic resistance in Neisseria gonorrhoeae.

Abstract

The susceptibility of 100 strains of Neisseria gonorrhoeae to five antimicrobial agents (penicillin, streptomycin, oxytetracycline, sulphamethoxazole, and gentamicin) was examined. Three strains were resistant to each antimicrobial, fourteen exhibited resistance to three or four of the five compounds tested, and 49 were resistant to a single agent, or to pairs of the selected agents. 34 strains were found to be fully sensitive to all of the compounds tested. It is suggested that resistance to gentamicin and sulphamethoxazole may be determined by a multiple resistance gene. The overall frequency of penicillin resistance was found to be 26-5 per cent (MIC greater than 0-06 mug/ml.), suggesting a significant decrease in resistance since 1968.

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Year: 1976 PMID： 827327 PMCID： PMC1045315 DOI： 10.1136/sti.52.6.384

Source DB: PubMed Journal: Br J Vener Dis ISSN： 0007-134X

19 in total

1. A comparison of the in vitro sensitivity of gonococci to penicillin with the results of treatment.

Authors: F R CURTIS; A E WILKINSON
Journal: Br J Vener Dis Date: 1958-06

2. Single-session treatment of uncomplicated gonorrhoea in men, using penicillin combined with cotrimoxazole. Controlled trial comparing four different treatment schedules with observations on antibiotic sensitivities of gonococci and a review of the literature.

Authors: A S Wigfield; J B Selkon; G E Rich
Journal: Br J Vener Dis Date: 1973-06

4. Neisseria gonorrhoeae isolates from Ethiopia 2. Pair correlations between minimal inhibitory concentration values of five antibiotics and frequency of multiple antibiotic resistance.

Authors: M Gedebou; A Tassew
Journal: Bull World Health Organ Date: 1980 Impact factor: 9.408

5. Rectal gonorrhoea in male homosexuals. Presentation and therapy.

Authors: J L Fluker; P Deherogoda; D J Platt; A Gerken
Journal: Br J Vener Dis Date: 1980-12

6. Transfer of plasmid-borne beta-lactamase in Neisseria gonorrhoeae.

Authors: E S Baron; A K Saz; D J Kopecko; J A Wohlhieter
Journal: Antimicrob Agents Chemother Date: 1977-08 Impact factor: 5.191

6 in total

Prevalence of multiple antibiotic resistance in Neisseria gonorrhoeae.

1. A comparison of the in vitro sensitivity of gonococci to penicillin with the results of treatment.

2. Single-session treatment of uncomplicated gonorrhoea in men, using penicillin combined with cotrimoxazole. Controlled trial comparing four different treatment schedules with observations on antibiotic sensitivities of gonococci and a review of the literature.

3. Antibiotic sensitivity testing. Report of an international collaborative study.

4. Multiple antibiotic resistance due to a single mutation in Neisseria gonorrhoeae.

5. In-vitro activity of twelve antibacterial agents against Neisseria gonorrhoeae.

6. Vancomycin-sensitive strains of Neisseria gonorrhoeae. A problem for the diagnostic laboratory.

7. Antibiotic disk susceptibility tests with Neisseria gonorrhoeae.

8. Neisseria meningitidis in urogenital infection.

9. The preservation of gonococci in liquid nitrogen.

10. Susceptibility of Neisseria gonorrhoeae to penicillin and tetracycline.

1. Inhibition of gonococci by a selective medium: disparity between isolates from sexual partners.

2. In vitro susceptibility of 50 non-beta-lactamase-producing Neisseria gonorrhoeae strains to 12 antimicrobial agents.

3. Auxotypes and antibacterial resistance to gonococci with differing susceptibilities to vancomycin.

4. Neisseria gonorrhoeae isolates from Ethiopia 2. Pair correlations between minimal inhibitory concentration values of five antibiotics and frequency of multiple antibiotic resistance.

5. Rectal gonorrhoea in male homosexuals. Presentation and therapy.

6. Transfer of plasmid-borne beta-lactamase in Neisseria gonorrhoeae.