| Literature DB >> 8268415 |
R Costello1, J Imbert, D Olive.
Abstract
IL-7 is a single-chain 25 kDa protein first identified in bone marrow cultures through its pre-B cell growth factor properties, then also described as a potent T-lymphocyte growth factor. This review relates to the molecular and functional aspects of interleukin-7 (IL-7) and its receptor (IL-7R). We focused on the role of IL-7 in T-cell activation, cytotoxicity generation, leukemic cell growth and immunotherapy.Entities:
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Year: 1993 PMID： 8268415
Source DB: PubMed Journal: Eur Cytokine Netw ISSN： 1148-5493 Impact factor: 2.737