Literature DB >> 8265655

Transcriptional regulatory elements downstream of the JunB gene.

E D Perez-Albuerne1, G Schatteman, L K Sanders, D Nathans.   

Abstract

JunB is an immediate early transcription factor that is induced by a variety of extracellular signaling agents, including growth factors, phorbol esters, and agents that elevate cyclic AMP. The mechanism of activation of the gene encoding JunB by these agents is not well understood. By using the JunB gene together with flanking DNA in transfection experiments, we show that a serum response element (SRE) and/or a cAMP response element (CRE) downstream of the gene mediate the response of the gene in mouse NIH 3T3 cells to serum, platelet-derived growth factor, basic fibroblast growth factor, phorbol ester, and forskolin. In addition, a segment of DNA just upstream of the TATA box is required for optimal activation of the gene.

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Year:  1993        PMID： 8265655      PMCID： PMC48105          DOI： 10.1073/pnas.90.24.11960

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  21 in total

1.  CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements.

Authors:  B Luckow; G Schütz
Journal:  Nucleic Acids Res       Date:  1987-07-10       Impact factor: 16.971

2.  The ability of a ternary complex to form over the serum response element correlates with serum inducibility of the human c-fos promoter.

Authors:  P E Shaw; H Schröter; A Nordheim
Journal:  Cell       Date:  1989-02-24       Impact factor: 41.582

3.  A gene activated by growth factors is related to the oncogene v-jun.

Authors:  K Ryder; L F Lau; D Nathans
Journal:  Proc Natl Acad Sci U S A       Date:  1988-03       Impact factor: 11.205

4.  Oligonucleotide-directed mutagenesis: a simple method using two oligonucleotide primers and a single-stranded DNA template.

Authors:  M J Zoller; M Smith
Journal:  Methods Enzymol       Date:  1987       Impact factor: 1.600

5.  Enhanced jun gene expression is an early genomic response to transforming growth factor beta stimulation.

Authors:  L Pertovaara; L Sistonen; T J Bos; P K Vogt; J Keski-Oja; K Alitalo
Journal:  Mol Cell Biol       Date:  1989-03       Impact factor: 4.272

6.  Induction of protooncogene c-jun by serum growth factors.

Authors:  K Ryder; D Nathans
Journal:  Proc Natl Acad Sci U S A       Date:  1988-11       Impact factor: 11.205

7.  Convulsant-induced increase in transcription factor messenger RNAs in rat brain.

Authors:  D W Saffen; A J Cole; P F Worley; B A Christy; K Ryder; J M Baraban
Journal:  Proc Natl Acad Sci U S A       Date:  1988-10       Impact factor: 11.205

8.  Two cis-regulatory elements that mediate different signaling pathways for serum-dependent activation of the junB gene.

Authors:  I Kitabayashi; Z Kawakami; T Matsuoka; R Chiu; G Gachelin; K Yokoyama
Journal:  J Biol Chem       Date:  1993-07-05       Impact factor: 5.157

9.  DNA binding activities of three murine Jun proteins: stimulation by Fos.

Authors:  Y Nakabeppu; K Ryder; D Nathans
Journal:  Cell       Date:  1988-12-02       Impact factor: 41.582

10.  Structure, chromosome location, and expression of the mouse zinc finger gene Krox-20: multiple gene products and coregulation with the proto-oncogene c-fos.

Authors:  P Chavrier; U Janssen-Timmen; M G Mattéi; M Zerial; R Bravo; P Charnay
Journal:  Mol Cell Biol       Date:  1989-02       Impact factor: 4.272
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  17 in total

1.  BMP enhances transcriptional responses to NGF during PC12 cell differentiation.

Authors:  P Lönn; K Zaia; C Israelsson; S Althini; D Usoskin; A Kylberg; T Ebendal
Journal:  Neurochem Res       Date:  2005 Jun-Jul       Impact factor: 3.996

2.  Serum response factor binding sites differ in three human cell types.

Authors:  Sara J Cooper; Nathan D Trinklein; Loan Nguyen; Richard M Myers
Journal:  Genome Res       Date:  2007-01-02       Impact factor: 9.043

3.  Multivalent DNA-binding properties of the HMG-1 proteins.

Authors:  J F Maher; D Nathans
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-25       Impact factor: 11.205

4.  MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts.

Authors:  Giselle R Wiggin; Ana Soloaga; Julia M Foster; Victoria Murray-Tait; Philip Cohen; J Simon C Arthur
Journal:  Mol Cell Biol       Date:  2002-04       Impact factor: 4.272

5.  Human T-cell leukemia virus type 1 Tax enhances serum response factor DNA binding and alters site selection.

Authors:  Heather Y Winter; Susan J Marriott
Journal:  J Virol       Date:  2007-03-21       Impact factor: 5.103

6.  A new platelet-derived growth factor-regulated genomic element which binds a serine/threonine phosphoprotein mediates induction of the slow immediate-early gene MCP-1.

Authors:  R R Freter; J A Alberta; K K Lam; C D Stiles
Journal:  Mol Cell Biol       Date:  1995-01       Impact factor: 4.272

7.  Expression and activity of serum response factor is required for expression of the muscle-determining factor MyoD in both dividing and differentiating mouse C2C12 myoblasts.

Authors:  C Gauthier-Rouviere; M Vandromme; D Tuil; N Lautredou; M Morris; M Soulez; A Kahn; A Fernandez; N Lamb
Journal:  Mol Biol Cell       Date:  1996-05       Impact factor: 4.138

8.  Platelet-derived growth factor-stimulated expression of the MCP-1 immediate-early gene involves an inhibitory multiprotein complex.

Authors:  P Sridhar; Y Liu; L D Chin; C E Borja; M Mann; H A Skopicki; R R Freter
Journal:  Mol Cell Biol       Date:  1999-06       Impact factor: 4.272

9.  Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression.

Authors:  Kim Ravnskjaer; Henri Kester; Yi Liu; Xinmin Zhang; Dong Lee; John R Yates; Marc Montminy
Journal:  EMBO J       Date:  2007-05-03       Impact factor: 11.598

10.  Identification of a functional promoter element in the 5'-flanking region of the rat cMG1/TIS11b gene.

Authors:  A N Corps; J C Pascall; K M Hadfield; K D Brown
Journal:  Biochem J       Date:  1995-10-01       Impact factor: 3.857
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