Literature DB >> 826344

[Parathion axial teratogenesis after giving several compounds with known anti-teratogenic or antitoxic properties in vertebrate adults or embryos after exposure to organic phosphates. Study in the quail embryo (Coturnix coturnix japonica)].

R Meiniel.   

Abstract

Axial abnormalities, highly specific of parathion, are prevented by pyridine aldoximes P2S, 2-PAM and TMB4. Atropine, well known as an antimuscarinic agent is ineffective and so it is for tryptophan and DMSO, compounds having protective effect on some morphogenetic disturbances induced by organic phosphates. These results point out the specificity of pyridine aldoximes as alleviating agents on the characteristic axial deformities induced by parathion.

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Year:  1976        PMID: 826344

Source DB:  PubMed          Journal:  C R Acad Hebd Seances Acad Sci D


  1 in total

1.  [Neuroactive compounds and vertebral teratogenesis in the bird embryo (author's transl)].

Authors:  R Meiniel
Journal:  Experientia       Date:  1978-03-15
  1 in total

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